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四种奥芬达唑制剂对牛线虫的疗效评估。

Evaluation of four forms of oxfendazole against nematodes of cattle.

作者信息

Todd K S, Mansfield M E

出版信息

Am J Vet Res. 1979 Mar;40(3):423-4.

PMID:475099
Abstract

Oxfendazole, methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl] carbamate, was evaluated in calves naturally infected with endoparasites. The compound was used as a drench, a paste, a bolus, and as top-dress crumbles at a dosage of 2.5 mg/kg of body weight. The four formulations produced similar effects and were 99% to 100% effective in removing the following adult parasite genera: Haemonchus, Ostertagia, Trichostrongylus. Cooperia, Bunostomum, Oesophagostomum, and Dictyocaulus. Mean efficacy against Trichuris spp varied from 87% to 95%, depending on the formulation used.

摘要

奥芬达唑,即甲基[5-(苯基亚磺酰基)-1H-苯并咪唑-2-基]氨基甲酸酯,在自然感染体内寄生虫的犊牛身上进行了评估。该化合物以2.5毫克/千克体重的剂量用作灌服剂、糊剂、大丸剂和撒施碎粒剂。这四种剂型产生了相似的效果,在清除以下成虫寄生虫属方面的有效性达99%至100%:血矛线虫属、奥斯特他线虫属、毛圆线虫属、古柏线虫属、牛仰口线虫属、食道口线虫属和网尾线虫属。对毛首线虫属的平均有效性因所用剂型而异,为87%至95%。

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