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麻疹患儿PHA刺激的白细胞培养物中的多核巨细胞。

Multinucleated giant cells in PHA-stimulated leucocyte cultures of children with measles.

作者信息

Osunkoya B O, Oyediran A B, Cooke A

出版信息

Immunology. 1973 Oct;25(4):737-42.

PMID:4753405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1423140/
Abstract

Multinucleated giant cells were seen in 3-day leucocyte cultures from some children with measles. The production of the giant cells was PHA dependent, and therefore constitute another form of abnormal PHA response by leucocytes .

摘要

在一些患麻疹儿童的3日龄白细胞培养物中可见多核巨细胞。巨细胞的产生依赖于PHA，因此构成白细胞异常PHA反应的另一种形式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/3172f0774d8c/immunology00333-0194-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/ec2169f178ea/immunology00333-0193-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/6e42d45bead8/immunology00333-0193-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/3172f0774d8c/immunology00333-0194-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/ec2169f178ea/immunology00333-0193-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/6e42d45bead8/immunology00333-0193-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8fa/1423140/3172f0774d8c/immunology00333-0194-a.jpg

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1
Multinucleated giant cells in PHA-stimulated leucocyte cultures of children with measles.麻疹患儿PHA刺激的白细胞培养物中的多核巨细胞。
Immunology. 1973 Oct;25(4):737-42.
2
Evidence that circulating lymphocytes act as vehicles or viraemia in measles.有证据表明循环淋巴细胞在麻疹中充当病毒载体或导致病毒血症。
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3
Cell-mediated immune reactions in measles.麻疹中的细胞介导免疫反应。
Acta Virol. 1980 Mar;24(2):119-26.
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Blood lymphocytes and measles viraemia.血液淋巴细胞与麻疹病毒血症
Afr J Med Med Sci. 1987 Dec;16(4):181-6.
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Studies on leukocyte cultures in measles. I. Lymphocyte transformation and giant cell formation in leukocyte cultures from clinical cases of measles.麻疹白细胞培养的研究。I. 麻疹临床病例白细胞培养中的淋巴细胞转化和巨细胞形成。
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Dynamics of morphologic changes of peripheral blood leukocytes cultured in vitro in the presence of phytohemagglutinin (PHA).在植物血凝素（PHA）存在的情况下体外培养的外周血白细胞形态变化的动力学
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The effect of cyclic AMP and related compounds on human lymphocyte transformation (HLT) stimulated by phytohemagglutinin (PHA).环磷酸腺苷及相关化合物对植物血凝素（PHA）刺激的人淋巴细胞转化（HLT）的影响。
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PHA-induced lymphocyte transformations in leucocyte cultures from malarious, malnourished and control Gambian children.来自冈比亚患疟疾、营养不良儿童及对照儿童的白细胞培养物中，PHA诱导的淋巴细胞转化
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引用本文的文献

1
Reversible repression and activation of measles virus infection in neural cells.神经细胞中麻疹病毒感染的可逆性抑制与激活
Proc Natl Acad Sci U S A. 1982 Mar;79(5):1629-33. doi: 10.1073/pnas.79.5.1629.
2
Studies on leukocyte cultures in measles. II. Detection of measles virus antigen in human leucocytes by immunofluorescence.麻疹患者白细胞培养的研究。II. 用免疫荧光法检测人白细胞中的麻疹病毒抗原。
Arch Gesamte Virusforsch. 1974;44(4):323-9. doi: 10.1007/BF01251013.
3
Studies on leukocyte cultures in measles. I. Lymphocyte transformation and giant cell formation in leukocyte cultures from clinical cases of measles.

本文引用的文献

1
MORPHOLOGICAL STUDIES IN THE CULTURE OF HUMAN LEUCOCYTES WITH PHYTOHAEMAGGLUTININ.用植物血凝素培养人白细胞的形态学研究
Br J Haematol. 1965 Jul;11:488-97. doi: 10.1111/j.1365-2141.1965.tb06613.x.
2
CYTOCHEMICAL STUDIES ON CELLS FROM CHRONIC LYMPHOCYTIC LEUKAEMIA AND LYMPHOSARCOMA CULTURE WITH PHYTOHAEMAGGLUTININ.慢性淋巴细胞白血病和淋巴肉瘤细胞经植物血凝素培养后的细胞化学研究
Br J Haematol. 1964 Jul;10:358-64. doi: 10.1111/j.1365-2141.1964.tb00712.x.
3
[ACTION OF PHYTOHEMAGGLUTININ "IN VITRO" ON THE LYMPHOCYTES OF CHRONIC LYMPHOID LEUKEMIA].
麻疹白细胞培养的研究。I. 麻疹临床病例白细胞培养中的淋巴细胞转化和巨细胞形成。
Arch Gesamte Virusforsch. 1974;44(4):313-22.
[植物血凝素“体外”对慢性淋巴细胞白血病淋巴细胞的作用]
Nouv Rev Fr Hematol. 1964 Jan-Feb;4:69-76.
4
Effects of phytohemagglutinin on rat and normal and leukemic human blood cells.植物血凝素对大鼠以及正常和白血病人类血细胞的作用。
Proc Soc Exp Biol Med. 1963 May;113:191-4. doi: 10.3181/00379727-113-28317.
5
In vivo and in vitro cellular changes specific for measles.麻疹特有的体内和体外细胞变化。
AMA Arch Pathol. 1958 Jun;65(6):587-99.
6
Studies with measles virus. I. Propagation in different tissue culture systems.麻疹病毒研究。I. 在不同组织培养系统中的增殖
J Immunol. 1957 May;78(5):330-40.
7
Propagation in tissue cultures of cytopathogenic agents from patients with measles.麻疹患者细胞病变病原体在组织培养中的传播。
Proc Soc Exp Biol Med. 1954 Jun;86(2):277-86. doi: 10.3181/00379727-86-21073.
8
Impaired in vitro lymphocyte transformation in Hodgkin's disease.霍奇金病患者体外淋巴细胞转化受损。
N Engl J Med. 1965 Nov 4;273(19):1006-12. doi: 10.1056/NEJM196511042731903.
9
Studies of the delayed response of phytohemagglutinin (PHA) stimulated lymphocytes in 25 chronic lymphatic leukemia patients before and during therapy.对25例慢性淋巴细胞白血病患者在治疗前及治疗期间进行的植物血凝素（PHA）刺激淋巴细胞延迟反应的研究。
Blood. 1969 Aug;34(2):166-78.
10
The delayed response of c0ronic lymphocytic leukemia lymphocytes to phytohemagglutinin in vitro.慢性淋巴细胞白血病淋巴细胞在体外对植物血凝素的延迟反应。
Proc Soc Exp Biol Med. 1968 Mar;127(3):668-71. doi: 10.3181/00379727-127-32769.