洗必泰从新生儿完整皮肤的吸收情况。
Absorption of chlorhexidine from the intact skin of newborn infants.
作者信息
Cowen J, Ellis S H, McAinsh J
出版信息
Arch Dis Child. 1979 May;54(5):379-83. doi: 10.1136/adc.54.5.379.
Abstract
34 newborn infants who had been bathed in a standard manner with Hibiscrub were studied to find out whether it was absorbed percutaneously. Low levels of chlorhexidine were found in the blood of all 10 babies sampled by heel prick, and 5 of 24 from whom venous blood was taken. The detection of chlorhexidine varied greatly with the method and timing of sampling, and no correlation was found between gestational or postnatal age and chlorhexidine levels.
摘要
对34名以标准方式用 Hibiscrub 沐浴的新生儿进行了研究，以确定其是否经皮吸收。在所有10名足跟采血的婴儿以及24名采静脉血的婴儿中的5名婴儿的血液中发现了低水平的氯己定。氯己定的检测结果因采样方法和时间的不同而有很大差异，并且未发现胎龄或出生后年龄与氯己定水平之间存在相关性。
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