冰岛绵羊小肠癌。一项病理学和流行病学研究。
Carcinoma of the small intestine of sheep in Iceland. A pathological and epizootiological study.
作者信息
Georgsson G, Vigfússon H
出版信息
Acta Vet Scand. 1973;14(3):392-409. doi: 10.1186/BF03547427.
Abstract
This paper deals with an unusually high incidence, i.e. 0.97 of carcinoma of the small intestine found in Icelandic sheep. The tumours were situated in the jejunum and upper ileum. The macroscopic and microscopic pathology is described and compared with carcinoma of the small intestine of domestic animals and humans. Aetiological factors are discussed and the possibility of exposure to carcinogenic substances, especially nitrosamines in food concentrates, is suggested. Finally these findings are discussed in relation to current ideas on carcinogenesis in the intestines.
摘要
本文探讨了冰岛绵羊中发现的小肠癌异常高的发病率，即0.97%。肿瘤位于空肠和回肠上段。描述了宏观和微观病理学，并与家畜和人类的小肠癌进行了比较。讨论了病因学因素，并提出了接触致癌物质的可能性，特别是浓缩饲料中的亚硝胺。最后，结合当前关于肠道致癌作用的观点对这些发现进行了讨论。
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