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Kinetics of diphenylhydantoin elimination in rats.

作者信息

Ashley J J, Levy G

出版信息

J Pharmacokinet Biopharm. 1973 Apr;1(2):99-102. doi: 10.1007/BF01059624.

DOI:10.1007/BF01059624
PMID:4764428
Abstract
摘要

相似文献

1
Kinetics of diphenylhydantoin elimination in rats.
J Pharmacokinet Biopharm. 1973 Apr;1(2):99-102. doi: 10.1007/BF01059624.
2
Effect of sulphonylureas (tolazamide, tolbutamide and chlorpropamide) on the metabolism of diphenylhydantoin in the rat.磺酰脲类药物（妥拉磺脲、甲苯磺丁脲和氯磺丙脲）对大鼠体内苯妥英代谢的影响。
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Effect of an inhibitor of glucuronide formation on elimination kinetics of diphenylhydantoin in rats.葡糖醛酸苷形成抑制剂对大鼠苯妥英钠消除动力学的影响。
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Conversion of phenytoin to reactive metabolites in rat liver microsomes.苯妥英在大鼠肝脏微粒体中转化为活性代谢物。
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引用本文的文献

1
The Bateman function revisited: a critical reevaluation of the quantitative expressions to characterize concentrations in the one compartment body model as a function of time with first-order invasion and first-order elimination.重新审视贝特曼函数：对单室体内模型中作为时间函数的浓度进行定量表达的批判性重新评估，该模型具有一级侵入和一级消除过程。
J Pharmacokinet Biopharm. 1994 Apr;22(2):103-28. doi: 10.1007/BF02353538.
2
Linear and nonlinear kinetics of drug elimination. I. Kinetics on the basis of a single capacity-limited pathway of elimination with or without simultaneous supply-limited elimination.
J Pharmacokinet Biopharm. 1974 Oct;2(5):395-415. doi: 10.1007/BF01071310.
3
Formation of active metabolites of anticonvulsant drugs. A review of their pharmacokinetic and therapeutic significance.抗惊厥药物活性代谢物的形成。其药代动力学及治疗意义综述。

本文引用的文献

1
Studies on the metabolism of diphenylhydantoin in mice.
J Pharmacol Exp Ther. 1969 May;167(1):77-90.
2
Study of dose-dependent metabolism of 5,5-diphenyl-hydantoin in the rat using new methodology for isolation and quantitation of metabolites in vivo and in vitro.使用体内和体外代谢物分离与定量新方法对大鼠体内5,5-二苯基乙内酰脲的剂量依赖性代谢进行研究。
J Pharmacol Exp Ther. 1971 Sep;178(3):567-79.
3
The rate of decline of diphenylhydantoin in human plasma.人体血浆中苯妥英的下降速率。
Clin Pharmacol Ther. 1970 Jan-Feb;11(1):121-34. doi: 10.1002/cpt1970111121.
Clin Pharmacokinet. 1991 Jul;21(1):27-41. doi: 10.2165/00003088-199121010-00003.
4
Inhibition of diphenylhydantoin elimination by its major metabolite.
Res Commun Chem Pathol Pharmacol. 1972 Sep;4(2):297-306.
5
Explanation of dose-dependent decline of diphenylhydantoin plasma levels by fitting to the integrated form of the Michaelis-Menten equation.通过拟合米氏方程的积分形式来解释苯妥英血浆水平的剂量依赖性下降。
Res Commun Chem Pathol Pharmacol. 1972 May;3(3):455-66.
6
Dose-dependence of drug plasma level decline in dogs.犬类药物血浆水平下降的剂量依赖性。
J Pharmacol Exp Ther. 1967 Nov;158(2):305-16.