• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Linear and nonlinear kinetics of drug elimination. I. Kinetics on the basis of a single capacity-limited pathway of elimination with or without simultaneous supply-limited elimination.

作者信息

van Ginneken C A, van Rossum J M, Fleuren H L

出版信息

J Pharmacokinet Biopharm. 1974 Oct;2(5):395-415. doi: 10.1007/BF01071310.

DOI:10.1007/BF01071310
PMID:4452943
Abstract
摘要

相似文献

1
Linear and nonlinear kinetics of drug elimination. I. Kinetics on the basis of a single capacity-limited pathway of elimination with or without simultaneous supply-limited elimination.
J Pharmacokinet Biopharm. 1974 Oct;2(5):395-415. doi: 10.1007/BF01071310.
2
Criticism of pharmacokinetic clearance concepts.对药代动力学清除概念的批评。
Int J Clin Pharmacol Ther Toxicol. 1983 Nov;21(11):563-8.
3
[Clinical pharmacokinetics--theoretical bases].
Ned Tijdschr Geneeskd. 1986 Jan 11;130(2):54-9.
4
Factors affecting drug biotransformation.影响药物生物转化的因素。
Clin Biochem. 1986 Apr;19(2):72-5. doi: 10.1016/s0009-9120(86)80051-0.
5
A discussion of drug metabolism and actions in the aged.
Drug Nutr Interact. 1985;4(1-2):99-106.
6
[First-pass effect as a therapeutic problem].
Pol Tyg Lek. 1983 Apr 18;38(16):511-4.
7
Model independent derivation of general equations for the "first-pass" effect and extra-hepatic drug elimination.“首过”效应和肝外药物消除通用方程的模型无关推导。
Eur J Clin Pharmacol. 1977;11(1):57-64. doi: 10.1007/BF00561789.
8
Contribution of lungs to total body clearance: linear and nonlinear effects.肺对全身清除率的贡献：线性和非线性效应。
J Pharm Sci. 1982 Jan;71(1):66-70. doi: 10.1002/jps.2600710117.
9
Drug therapy: drug disposition in old age.药物治疗：老年人的药物处置
N Engl J Med. 1982 May 6;306(18):1081-8. doi: 10.1056/NEJM198205063061804.
10
Practical pharmacokinetics as part of clinical pharmacology.实用药代动力学作为临床药理学的一部分。
Int Z Klin Pharmakol Ther Toxikol. 1970 Dec;4(1):37-41.

引用本文的文献

1
Barriers to Building More Effective Treatments: Negative Interactions Amongst Smoking Intervention Components.构建更有效治疗方法的障碍：吸烟干预各组成部分之间的负面相互作用
Clin Psychol Sci. 2021 Nov 1;9(6):995-1020. doi: 10.1177/2167702621994551. Epub 2021 Apr 26.
2
Evaluation of Lidocaine and Metabolite Pharmacokinetics in Hyaluronic Acid Injection.透明质酸注射中利多卡因及其代谢物的药代动力学评估。
Pharmaceutics. 2021 Feb 2;13(2):203. doi: 10.3390/pharmaceutics13020203.
3
Dose-dependent absorption and elimination of gamma-hydroxybutyric acid in healthy volunteers.

本文引用的文献

1
The kinetics of alcohol elimination in man.人体中酒精消除的动力学。
Acta Pharmacol Toxicol (Copenh). 1958;14(3):265-89. doi: 10.1111/j.1600-0773.1958.tb01164.x.
2
Metabolic disposition of diphenylhydantoin in normal human subjects following intravenous administration.静脉注射后苯妥英在正常人体中的代谢情况。
Clin Pharmacol Ther. 1969 Jul-Aug;10(4):498-504. doi: 10.1002/cpt1969104498.
3
Kinetics of diphenylhydantoin elimination in rats.
J Pharmacokinet Biopharm. 1973 Apr;1(2):99-102. doi: 10.1007/BF01059624.
健康志愿者中γ-羟基丁酸的剂量依赖性吸收与消除
Eur J Clin Pharmacol. 1993;45(4):353-6. doi: 10.1007/BF00265954.
4
Disposition of azole antifungal agents. II. Hepatic binding and clearance of dichlorophenyl-bis-triazolylpropanol (DTP) in the rat.唑类抗真菌剂的处置。II. 大鼠体内二氯苯基-双三唑基丙醇（DTP）的肝脏结合与清除
Pharm Res. 1994 Jul;11(7):951-60. doi: 10.1023/a:1018966800208.
5
Measurement of excretion characteristics of theophylline and its major metabolites.茶碱及其主要代谢产物排泄特征的测定。
Eur J Clin Pharmacol. 1981;20(6):435-41. doi: 10.1007/BF00542096.
6
Simultaneous kinetic modelling of plasma levels and urinary excretion of salicyluric acid, and the influence of probenecid.
Eur J Drug Metab Pharmacokinet. 1983 Jul-Sep;8(3):239-49. doi: 10.1007/BF03188754.
7
Non-linear kinetics of 4-methylpyrazole in healthy human subjects.4-甲基吡唑在健康人体中的非线性动力学
Eur J Clin Pharmacol. 1989;37(6):599-604. doi: 10.1007/BF00562552.
8
Saturable pharmacokinetics in the renal excretion of drugs.药物经肾排泄的饱和药代动力学
Clin Pharmacokinet. 1989 Jan;16(1):38-54. doi: 10.2165/00003088-198916010-00003.
9
Do you need a pharmacokinetic model, and, if so, which one?你需要一个药代动力学模型吗？如果需要，是哪一种呢？
J Pharmacokinet Biopharm. 1975 Dec;3(6):457-78. doi: 10.1007/BF01059477.
4
Properties of the Michaelis-Menten equation and its integrated form which are useful in pharmacokinetics.米氏方程及其积分形式在药代动力学中有用的性质。
J Pharmacokinet Biopharm. 1973 Apr;1(2):103-21. doi: 10.1007/BF01059625.
5
Variations in absorption and elimination rates of ethyl alcohol in a single subject.
Res Commun Chem Pathol Pharmacol. 1972 Jul;4(1):61-76.
6
Limited capacity for salicyl phenolic glucuronide formation and its effect on the kinetics of salicylate elimination in man.
Clin Pharmacol Ther. 1972 Mar-Apr;13(2):258-68. doi: 10.1002/cpt1972132258.
7
Liver adaptation and injury in alcoholism.
N Engl J Med. 1973 Feb 15;288(7):356-62. doi: 10.1056/NEJM197302152880710.