Köhl U, Lob M
Schweiz Med Wochenschr. 1975 Jan 11;105(2):50-56.
Clinical and physiologic data on chronic carbon monoxide poisoning are reviewed and the results of an investigation involving 7 garages in the Lausanne (Switzerland) area are reported. The aim was a practical approach to the relationships between carbon monoxide level in the air, COHb and clinical picture. The study covered working conditions (especially ventilation) but did not take into account of other factors (stresses) which may effect the parameters investigated. CO was measured by continuous recording with an MSA Carbon Monoxide Alarm and the hourly and daily averages were determined. The garage personnel replied to a questionnaire and underwent a brief clinical examination including taking of digital blood samples for measurement of hematocrit and carboxyhemoglobin level by the method of COMMINS and LAWTHER as modified by BUCHWALD. One of the garages did not meet present health requirements. Statistical analysis revealed a significant correlation between carbon monoxide and carboxyhemoglobin. The incidence of complaints was highest in poorly ventilated garages. On the basis of COHb level in the total group of employees, together with data from individual histories, it is possible to evaluate the risk of carbon monoxide poisoning in a given garage.
本文回顾了慢性一氧化碳中毒的临床和生理数据,并报告了一项对瑞士洛桑地区7个车库的调查结果。目的是探讨空气中一氧化碳水平、碳氧血红蛋白(COHb)与临床表现之间的实际关系。该研究涵盖了工作条件(特别是通风情况),但未考虑其他可能影响所研究参数的因素(压力)。使用MSA一氧化碳报警器连续记录来测量一氧化碳,并确定每小时和每日的平均值。车库工作人员回答了一份问卷,并接受了简短的临床检查,包括采集指尖血样,采用经布赫瓦尔德修改的康明斯和劳瑟方法测量血细胞比容和碳氧血红蛋白水平。其中一个车库不符合当前的健康要求。统计分析显示一氧化碳与碳氧血红蛋白之间存在显著相关性。通风不良的车库中投诉发生率最高。根据全体员工的碳氧血红蛋白水平以及个人病史数据,可以评估特定车库中一氧化碳中毒的风险。