• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Determination of nanogram quantities of diphenhydramine and orphenadrine in human plasma using gas-liquid chromatography.

作者信息

Bilzer W, Gundert-Remy U

出版信息

Eur J Clin Pharmacol. 1973 Dec;6(4):268-70. doi: 10.1007/BF00644744.

DOI:10.1007/BF00644744
PMID:4777260
Abstract
摘要

相似文献

1
Determination of nanogram quantities of diphenhydramine and orphenadrine in human plasma using gas-liquid chromatography.采用气液色谱法测定人血浆中纳克量的苯海拉明和邻甲苯海明
Eur J Clin Pharmacol. 1973 Dec;6(4):268-70. doi: 10.1007/BF00644744.
2
Quantitative determination of diphenhydramine and orphenadrine in human serum by capillary gas chromatography.
J Clin Chem Clin Biochem. 1983 Oct;21(10):595-7. doi: 10.1515/cclm.1983.21.10.595.
3
Diphenhydramine determination in human plasma by gas-liquid chromatography using nitrogen-phosphorus detection: application to single low-dose pharmacokinetic studies.
J Pharm Sci. 1983 Aug;72(8):941-3. doi: 10.1002/jps.2600720825.
4
Sensitive and specific gas chromatographic and extraction method for the determination of orphenadrine in human body fluids.
J Chromatogr. 1977 Dec 1;144(2):201-8. doi: 10.1016/s0021-9673(00)99355-5.
5
Isothermal gas chromatographic analysis of diphenhydramine after direct injection onto a fused-silica capillary column.
J Chromatogr. 1984 May 11;307(2):295-304. doi: 10.1016/s0378-4347(00)84101-8.
6
Determination of diphenhydramine in biological fluids by capillary gas chromatography using nitrogen-phosphorus detection. Application to placental transfer studies in pregnant sheep.
J Chromatogr. 1986 Jun 13;378(2):385-93.
7
Simple and rapid GLC method for the determination of orphenadrine in human plasma.
Biomed Chromatogr. 1987;2(5):193-4. doi: 10.1002/bmc.1130020504.
8
Method for the determination of diphenhydramine in rabbit whole blood by high-performance liquid chromatography (HPLC) with ultraviolet (UV) detection in conjunction with gas chromatography (GC) with mass selective detection (MSD).
Pharm Res. 1992 Jul;9(7):929-32. doi: 10.1023/a:1015861218342.
9
A report on the analysis of orphenadrine in post mortem specimens.一份关于死后标本中奥芬那君分析的报告。
J Anal Toxicol. 1983 Mar-Apr;7(2):72-5. doi: 10.1093/jat/7.2.72.
10
Determination of diphenhydramine in plasma by gas chromatography.气相色谱法测定血浆中的苯海拉明。
Res Commun Chem Pathol Pharmacol. 1974 Jan;7(1):95-103.

引用本文的文献

1
Biodistribution of diphenhydramine in reproductive organs in an overdose case.一例过量用药病例中苯海拉明在生殖器官中的生物分布。
Hum Cell. 2017 Apr;30(2):106-116. doi: 10.1007/s13577-016-0151-9. Epub 2016 Nov 12.
2
Development of a capillary electrophoresis method for the determination of orphenadrine citrate in tablets in the presence of paracetamol.建立一种毛细管电泳法，用于在对乙酰氨基酚存在的情况下测定片剂中的柠檬酸奥芬那君。
Saudi Pharm J. 2010 Oct;18(4):233-7. doi: 10.1016/j.jsps.2010.07.007. Epub 2010 Aug 2.
3
A rapid method for the determination of diphenhydramine in plasma.

本文引用的文献

1
Levels for pyribenzamine and benadryl in blood and urine following a single orally administered dose.单次口服给药后血液和尿液中扑敏宁和苯海拉明的含量。
J Allergy. 1948 Jul;19(4):251-5. doi: 10.1016/0021-8707(48)90062-8.
一种测定血浆中苯海拉明的快速方法。
Br J Clin Pharmacol. 1976 Dec;3(6):1062-4. doi: 10.1111/j.1365-2125.1976.tb00360.x.
4
[Poisoning by diphenhydramine--forensic-toxicologic interpretation of analytic results ].[苯海拉明中毒——分析结果的法医学毒理学解读]
Z Rechtsmed. 1982;88(4):263-70. doi: 10.1007/BF00198661.
5
Lethal intoxication with diphenhydramine. Report of a case with analytical follow-up.
Arch Toxicol. 1983 May;53(1):33-9. doi: 10.1007/BF01459999.
6
Relationship between antihistamic activity and plasma level of diphenhydramine.
Eur J Clin Pharmacol. 1974 Aug 23;7(5):393-5. doi: 10.1007/BF00558213.
7
Clinical pharmacokinetics of anti-parkinsonian drugs.抗帕金森病药物的临床药代动力学
Clin Pharmacokinet. 1987 Sep;13(3):141-78. doi: 10.2165/00003088-198713030-00002.
8
Interactions of orphenadrine and phenobarbitone with chlorpromazine: plasma concentrations and effects in man.奥芬那君和苯巴比妥与氯丙嗪的相互作用：人体中的血浆浓度及效应
Br J Clin Pharmacol. 1975 Jun;2(3):197-208. doi: 10.1111/j.1365-2125.1975.tb01576.x.