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Reactivation of phosphorylated cholinesterases in vitro and protecting effects in vivo of some pyridinium and quinolinium oximes.

作者信息

Simeon V, Skrinjarić-Spoljar M, Wilhelm K

出版信息

Arh Hig Rada Toksikol. 1973 Jan;24(1):11-8.

PMID:4777978
Abstract
摘要

相似文献

1
Reactivation of phosphorylated cholinesterases in vitro and protecting effects in vivo of some pyridinium and quinolinium oximes.某些吡啶鎓和喹啉鎓肟在体外对磷酸化胆碱酯酶的重活化作用及在体内的保护作用。
Arh Hig Rada Toksikol. 1973 Jan;24(1):11-8.
2
[Relations between chemical structure and cholinesterase-reactivating effect in a series of new asymmetric pyridinium salts. II. 2-hydroximino-methylpyridine derivates].[一系列新型不对称吡啶鎓盐的化学结构与胆碱酯酶复活作用之间的关系。II. 2-羟基亚氨基甲基吡啶衍生物]
Arzneimittelforschung. 1970 Feb;20(2):197-200.
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[Traumatic shock and cholinesterase reactivators].[创伤性休克与胆碱酯酶复活剂]
Cas Lek Cesk. 1973 Feb;112(6):168-72.
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Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin.五种结构不同的乙酰胆碱酯酶复活剂对被环沙林抑制的人脑胆碱酯酶的复活效力。
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Reactivation of human brain homogenate cholinesterases inhibited by Tabun using newly developed oximes K117 and K127.
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Reactivation of isopropyl-methylphosphonylated acetylcholinesterase by , -bis-(4-hydroxyiminomethylpyridinium)-2-trans-butene dibromide. The effect of temperature.
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7
Tabun-inhibited rat tissue and blood cholinesterases and their reactivation with the combination of trimedoxime and HI-6 in vivo.体内三羟肟酸和双羟肟酸联合对敌敌畏抑制的大鼠组织和血液胆碱酯酶的复能作用。
Chem Biol Interact. 2010 Sep 6;187(1-3):287-90. doi: 10.1016/j.cbi.2010.02.009. Epub 2010 Feb 16.
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[Reactions of pyridinium oximes with the alkyl phosphate dimethoate and its derivatives. Effects upon cholinesterases].[吡啶肟与烷基磷酸酯乐果及其衍生物的反应。对胆碱酯酶的影响]
Biochim Biophys Acta. 1966 Nov 15;128(2):363-71.
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Synthesis and in vitro kinetic study of novel mono-pyridinium oximes as reactivators of organophosphorus (OP) inhibited human acetylcholinesterase (hAChE).新型单吡啶𬭩肟类化合物的合成及其对有机磷(OP)抑制的人乙酰胆碱酯酶(hAChE)的体外动力学研究。
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Combined approach to demonstrate acetylcholinesterase activity changes in the rat brain following tabun intoxication and its treatment.联合方法研究沙林中毒及其治疗后大鼠大脑中乙酰胆碱酯酶活性的变化。
Toxicol Mech Methods. 2012 Jan;22(1):60-6. doi: 10.3109/15376516.2011.596231. Epub 2011 Aug 19.

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The structural and biochemical impacts of monomerizing human acetylcholinesterase.单体化人乙酰胆碱酯酶的结构和生化影响。
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Dichlorvos-induced central apnea: effects of selective brainstem exposure in the rat.敌敌畏诱导的中枢性呼吸暂停:在大鼠中选择性脑干暴露的影响。
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