人血浆凝血因子XII中反应性半胱氨酸残基周围的氨基酸序列。
The amino acid sequence around the reactive cysteine residue in human plasma Factor XII.
作者信息
Holbrook J J, Cooke R D, Kingston I B
出版信息
Biochem J. 1973 Dec;135(4):901-3. doi: 10.1042/bj1350901.
Abstract
- Activated human plasma factor XIII was 65% inhibited by iodo[(14)C]acetate and incorporated 0.6 mol of label into the alpha subunit, which eventually was allowed to form a precipitate. 2. All the label was recovered as S-carboxymethylcysteine in a tetra-peptide of sequence Gly-Gln-Cys-Trp.
摘要
- 活化的人血浆因子XIII被碘代[（14）C]乙酸酯抑制了65%，并将0.6摩尔的标记物掺入α亚基中，该亚基最终形成沉淀。2. 所有标记物均以序列为甘氨酸-谷氨酰胺-半胱氨酸-色氨酸的四肽中的S-羧甲基半胱氨酸形式回收。
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