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小家鼠的染色体标记:C带的品系差异。

Chromosome markers in Mus musculus: strain differences in C-banding.

作者信息

Dev V G, Miller D A, Miller O J

出版信息

Genetics. 1973 Dec;75(4):663-70. doi: 10.1093/genetics/75.4.663.

Abstract

The mitotic chromosomes of several inbred strains of mice and a series of F(1) hybrids have been analyzed by quinacrine staining and further characterized by the centromeric heterochromatin banding (C-banding). Inbred strains had the same amount of C-banding material on homologous chromosomes but showed variation in the amount on different chromosomes. F(1) hybrids showed characteristics of each parent and it appears that the amount of C-banding on each chromosome is a simple inherited polymorphism. In this study 12 different chromosomes could be distinguished by their C-banding, and these can be used as normal chromosome markers.

摘要

通过喹吖因染色分析了几种近交系小鼠和一系列F(1)杂种的有丝分裂染色体,并通过着丝粒异染色质带型分析(C带)进一步进行了特征描述。近交系在同源染色体上具有相同数量的C带物质,但在不同染色体上的数量存在差异。F(1)杂种表现出每个亲本的特征,并且似乎每条染色体上的C带数量是一种简单遗传的多态性。在本研究中,12条不同的染色体可通过其C带加以区分,这些染色体可作为正常的染色体标记。

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