Pagnan A, Canterin A A, Donadon V, Rigatti S, Cignacco G B, Palù C D
G Ital Cardiol. 1979;9(5):472-9.
The cardiological centers of Pordenone and Cittadella (Italy) organized by the Institute of Clinica Medica II of Padua University, have carried out a study on the "Precursors of arteriosclerosis in children", according to a WHO protocol. In this paper some results of the Pordenone study are reported, concerning serum cholesterol (TC), triglycerides (TG) and blood glucose 1 h after 1 g/Kg glucose per os. 520 school children, males and females, aged 6, 9, 12, 15 years, entered the study. Mean serum TC resulted significantly higher at age 12 as compared to the other age classes. Serum TG progressively increased with age. Mean serum TC and TG in our italian children and adolescents were silimar to those reported in studies from other countries. Blood glucose resulted significantly higher in children than in adolescents. The distribution of the blood glucose values was bimodal. After having arbitrarily fixed cut-off points for serum TC, TG and blood glucose, the prevalence of hyperlipidemia and hyperglycemia was determined. The prevalence figures have shown that at the pediatric age it is possible to identify subjects at "risk" of developing arteriosclerosis.
由帕多瓦大学第二临床医学院组织的意大利波代诺内和奇塔代拉的心脏病学中心,按照世界卫生组织的方案,开展了一项关于“儿童动脉粥样硬化的先兆”的研究。本文报告了波代诺内研究的一些结果,涉及口服1克/千克葡萄糖后1小时的血清胆固醇(TC)、甘油三酯(TG)和血糖。520名6岁、9岁、12岁、15岁的男女生参与了该研究。与其他年龄段相比,12岁时的平均血清TC显著更高。血清TG随年龄逐渐升高。我们意大利儿童和青少年的平均血清TC和TG与其他国家研究报告的相似。儿童的血糖显著高于青少年。血糖值的分布呈双峰状。在任意设定血清TC、TG和血糖的切点后,确定了高脂血症和高血糖的患病率。患病率数据表明,在儿童时期就有可能识别出有患动脉粥样硬化“风险”的个体。