Stewart A M, Lennox E L, Sanders B M
Br J Cancer. 1973 Dec;28(6):568-74. doi: 10.1038/bjc.1973.187.
A study of 2072 children who developed cerebral or spinal cord tumours of varying degrees of malignancy before 15 years of age has shown that there is equally good representation of fatal and non-fatal cases in official registrations. Attack rates are higher for boys than girls and the prognosis is better for girls than boys. The risk of an early death is negatively correlated with age at diagnosis, and the risk of a late death shows the opposite relationship. These observations and a relatively high incidence of hindbrain tumours are suggestive of an embryonic origin for most of the cases.
一项针对2072名15岁前罹患不同恶性程度脑肿瘤或脊髓肿瘤的儿童的研究表明，官方登记中致命和非致命病例的代表性相当。男孩的发病率高于女孩，女孩的预后比男孩好。早期死亡风险与诊断时的年龄呈负相关，晚期死亡风险则呈现相反的关系。这些观察结果以及后脑肿瘤相对较高的发病率表明，大多数病例起源于胚胎。
