Morphological differences in cerebral cortex and corpus callosum are genetically determined in two different strains of mice.

A morphological analysis of the cerebral cortex and corpus callosum was performed in two inbred strins of mice (SEC/1ReJ and C57BL/6J) different for a number of inborn and acquired behavioral patterns and for their ontogenic behavioral development. The data obtained indicate that in these two strains there are clear differences in the total thickness in the medial-anterior cortical region and temporal region, in the thickness and cell grey coefficient of the layers II-III, IV and V of some areas of parietal and frontal regions, and in the thickness of corpus callosum. These findings are discussed in terms of possible correlations between brain structure and behavior.