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三磷酸腺苷对大鼠膈肌和青蛙缝匠肌肌纤维记录的终板电位的作用。

Action of adenosine triphosphate on endplate potentials recorded from muscle fibres of the rat-diaphragm and frog sartorius.

作者信息

Ribeiro J A, Walker J

出版信息

Br J Pharmacol. 1973 Dec;49(4):724-5. doi: 10.1111/j.1476-5381.1973.tb08555.x.

Abstract

Evoked and spontaneous endplate potentials (e.p.ps) were recorded with intracellular electrodes from fibres of the rat diaphragm and the frog sartorius muscle. The amplitudes of the evoked e.p.ps were reduced to about one-half their control values in the presence of 0.1 mm and 0.2 mm of adenosine triphosphate (ATP). The amplitude of the spontaneous endplate potentials (miniature e.p.ps) was unaffected by ATP but their frequency was reduced.

摘要

用细胞内电极记录大鼠膈肌和青蛙缝匠肌纤维的诱发终板电位(e.p.ps)和自发终板电位。在存在0.1毫米和0.2毫米三磷酸腺苷(ATP)的情况下,诱发e.p.ps的幅度降低至其对照值的约二分之一。自发终板电位(微小e.p.ps)的幅度不受ATP影响,但其频率降低。

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