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自闭症与大脑左右不对称异常

Autism and unfavorable left-right asymmetries of the brain.

作者信息

Hier D B, LeMay M, Rosenberger P B

出版信息

J Autism Dev Disord. 1979 Jun;9(2):153-9. doi: 10.1007/BF01531531.

DOI:10.1007/BF01531531
PMID:479099
Abstract

Utilizing computerized brain tomography, left-right morphologic asymmetries of the parietooccipital region were judged in 16 autistic patients, 44 mentally retarded patients, and 100 miscellaneous neurological patients. In 57% of the autistic patients the right parietooccipital region was wider than the left, while this pattern of cerebral asymmetry was found in only 23% of the mentally retarded patients and 25% of the neurological patients. It is suggested that unfavorable morphologic asymmetries of the brain near the posterior language zone may contribute to the difficulties autistic children experience in acquiring language.

摘要

利用计算机断层脑扫描技术,对16名自闭症患者、44名智力迟钝患者和100名其他神经疾病患者的顶枕区左右形态不对称情况进行了判断。在57%的自闭症患者中,右侧顶枕区比左侧宽,而这种脑不对称模式在智力迟钝患者中仅占23%,在神经疾病患者中占25%。有人提出,靠近后语言区的脑形态不对称可能是自闭症儿童在语言习得方面遇到困难的原因之一。

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1
Autism and unfavorable left-right asymmetries of the brain.自闭症与大脑左右不对称异常
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2
Unfavourable left-right asymmetries of the brain and autism: a question of methodology.
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Morphological cerebral asymmetries in autistic children.自闭症儿童的大脑形态不对称性。
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Childhood autism: An appeal for an integrative and psychobiological approach.儿童自闭症:呼吁采用综合心理生物学方法。
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本文引用的文献

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Organic factors in infantile psychoses and borderline psychoses. A retrospective study of 46 cases subjected to pneumoencephalography.婴儿期精神病和边缘性精神病中的器质性因素。对46例行气脑造影术病例的回顾性研究。
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自闭症患者感觉诱发电位中的皮质变异性。
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Psychological correlates of handedness and corpus callosum asymmetry in autism: the left hemisphere dysfunction theory revisited.自闭症中利手和胼胝体不对称的心理相关性:左半球功能障碍理论再探。
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Planum temporale volume in children and adolescents with autism.患有自闭症的儿童和青少年的颞平面体积
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