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自闭症与大脑左右不对称异常

Autism and unfavorable left-right asymmetries of the brain.

作者信息

Hier D B, LeMay M, Rosenberger P B

出版信息

J Autism Dev Disord. 1979 Jun;9(2):153-9. doi: 10.1007/BF01531531.

Abstract

Utilizing computerized brain tomography, left-right morphologic asymmetries of the parietooccipital region were judged in 16 autistic patients, 44 mentally retarded patients, and 100 miscellaneous neurological patients. In 57% of the autistic patients the right parietooccipital region was wider than the left, while this pattern of cerebral asymmetry was found in only 23% of the mentally retarded patients and 25% of the neurological patients. It is suggested that unfavorable morphologic asymmetries of the brain near the posterior language zone may contribute to the difficulties autistic children experience in acquiring language.

摘要

利用计算机断层脑扫描技术,对16名自闭症患者、44名智力迟钝患者和100名其他神经疾病患者的顶枕区左右形态不对称情况进行了判断。在57%的自闭症患者中,右侧顶枕区比左侧宽,而这种脑不对称模式在智力迟钝患者中仅占23%,在神经疾病患者中占25%。有人提出,靠近后语言区的脑形态不对称可能是自闭症儿童在语言习得方面遇到困难的原因之一。

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