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庆大霉素、卡那霉素、西索米星和妥布霉素这几种氨基糖苷类抗生素的纸片法与试管稀释法敏感性试验之间的相互关系。

Interrelationships between disk and tube dilution sensitivity tests for the aminoglycoside antibiotics gentamicin, kanamycin, sisomicin, and tobramycin.

作者信息

Waitz J A

出版信息

Antimicrob Agents Chemother. 1973 Oct;4(4):445-54. doi: 10.1128/AAC.4.4.445.

Abstract

Poor statistical correlation was obtained between tube dilution test results and disk test results by using standard procedures. Significant regressions were obtained although they were not linear. Different regressions were obtained with different bacterial species. It is suggested that for the aminoglycosides studied (gentamicin, kanamycin, tobramycin, and sisomicin) both disk and dilution tests are useful in separating resistant from sensitive organisms. However, poor relationships were obtained between the two test types among sensitive organisms.

摘要

采用标准程序时,试管稀释试验结果与纸片试验结果之间的统计相关性较差。尽管回归不呈线性,但仍得到了显著的回归关系。不同细菌种类得到了不同的回归关系。对于所研究的氨基糖苷类药物(庆大霉素、卡那霉素、妥布霉素和西索米星),纸片试验和稀释试验在区分耐药菌和敏感菌方面均有用。然而,在敏感菌中,两种试验类型之间的关系较差。

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