Cann C E, Prussin S G, Gordan G S
J Clin Endocrinol Metab. 1979 Oct;49(4):543-5. doi: 10.1210/jcem-49-4-543.
Aluminum-containing drugs are used extensively to bind dietary phosphate and as antacids, but little is known about toxicity and tissue uptake of ingested aluminum. Aluminum concentrations were measured by neutron activation analysis in tissues taken from hyperparathyroid and normal human subjects and from rats. The parathyroid glands contained significantly more aluminum per unit mass than did thyroid or cervical muscle. The concentration of aluminum in the parathyroids appears to be linearly related to dietary aluminum intake.
含铝药物被广泛用于结合膳食中的磷酸盐并用作抗酸剂，但对于摄入铝的毒性和组织摄取情况却知之甚少。通过中子活化分析测定了取自甲状旁腺功能亢进患者、正常人类受试者以及大鼠的组织中的铝浓度。甲状旁腺每单位质量所含的铝明显多于甲状腺或颈部肌肉。甲状旁腺中的铝浓度似乎与膳食铝摄入量呈线性相关。
