补体介导的免疫球蛋白与胰腺和肠道某些内分泌细胞的结合。
Complement-mediated binding of immunoglobulins to some endocrine cells of the pancreas and gut.
作者信息
Buffa R, Solcia E, Fiocca R, Crivelli O, Pera A
出版信息
J Histochem Cytochem. 1979 Sep;27(9):1279-80. doi: 10.1177/27.9.479571.
PMID:479571
Abstract
Unspecific binding of immunoglobulins to gastrin, somatostain and glucagon cells of the gastrointestinal mucosa or pancreas has been found to occur through a nonantigen-antibody mechanism mediated by the C14 fraction of complement. The phenomenon represents an important drawback in hormone immunohistochemistry, which can be overcome by using complement deprived, highly dilute anti-hormone sera.
摘要
已发现免疫球蛋白通过补体C14部分介导的非抗原-抗体机制，与胃肠道黏膜或胰腺的胃泌素、生长抑素和胰高血糖素细胞发生非特异性结合。这种现象是激素免疫组织化学中的一个重要缺陷，可通过使用去除补体的高度稀释抗激素血清来克服。
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