Konstantinova N A, Ostreĭko K K, Tumanova I A, Lavret'ev V V, Petrov R V
Biull Eksp Biol Med. 1982 Dec;94(12):73-5.
The complement-fixing capacity of aggregated immunoglobulins with varying molecular weights has been explored. It has been demonstrated that as the molecular weight of a complex rises, the complement-fixing capacity increases. The amount of unfixed complement depends nonlinearly on the concentration of complement added and aggregated complexes in solution. The size of the complexes rather than their concentration plays the key role in the measurement of the complement-fixing capacity of aggregated immunoglobulins.