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小鼠细胞系中干扰素产量的提高，小鼠干扰素的高产来源。

Enhancement of interferon production in mouse cell line, a high-yielding source of mouse interferon.

作者信息

Edy V G, Billiau A, De Somer P

出版信息

Appl Microbiol. 1973 Sep;26(3):434-6. doi: 10.1128/am.26.3.434-436.1973.

DOI:10.1128/am.26.3.434-436.1973
PMID:4796165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC379811/
Abstract

Priming with interferon prior to poly(I).poly(C) treatment of a mouse cell line, MO 57/2, followed by sequential administration of metabolic inhibitors, resulted in the production of high yields of mouse interferon.

摘要

在用聚肌苷酸-聚胞苷酸（poly(I).poly(C)）处理小鼠细胞系MO 57/2之前，先用干扰素进行预处理，然后依次给予代谢抑制剂，可产生高产率的小鼠干扰素。

相似文献

1
Enhancement of interferon production in mouse cell line, a high-yielding source of mouse interferon.小鼠细胞系中干扰素产量的提高，小鼠干扰素的高产来源。
Appl Microbiol. 1973 Sep;26(3):434-6. doi: 10.1128/am.26.3.434-436.1973.
2
On the mechanism of enhancement of human interferon production by actinomycin D and cycloheximide.放线菌素D和环己酰亚胺增强人干扰素产生的机制
Virology. 1976 Mar;70(1):256-9. doi: 10.1016/0042-6822(76)90267-1.
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Enhanced production of human interferon by u.v. irradiated cells.
J Gen Virol. 1974 Oct;25(1):147-50. doi: 10.1099/0022-1317-25-1-147.
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Mass production of human interferon in diploid cells.在二倍体细胞中大规模生产人干扰素。
In Vitro Monogr. 1974(3):39-46.
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Control of interferon synthesis: effect of diethylaminoethyl-dextran on induction by polyinosinic-polycytidylic acid.干扰素合成的调控：二乙氨基乙基葡聚糖对聚肌苷酸-聚胞苷酸诱导作用的影响
J Virol. 1972 Oct;10(4):614-21. doi: 10.1128/JVI.10.4.614-621.1972.
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Altered cellular responses to interferon induction by poly I-poly C: priming and hyporesponsiveness in cells treated with interferon preparations.聚肌苷酸-聚胞苷酸对干扰素诱导的细胞反应改变：用干扰素制剂处理的细胞中的启动作用和低反应性
Arch Gesamte Virusforsch. 1973;43(3):273-83.
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Induction and production of interferon.
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Correlation between the induction of mouse interferon and the amount of its mRNA.小鼠干扰素的诱导与其mRNA量之间的相关性。
Eur J Biochem. 1979 Jul;98(1):215-21. doi: 10.1111/j.1432-1033.1979.tb13179.x.
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Distinguishing characteristics of the interferon responses of primary and continuous mouse cell cultures.原代和连续传代小鼠细胞培养物干扰素反应的鉴别特征。
J Gen Virol. 1971 Oct;13(1):35-50. doi: 10.1099/0022-1317-13-1-35.
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Effect of metabolic inhibitors on viral and polynucleotide induction of chick cell interferon.
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引用本文的文献

1
Immune (gamma) interferon production by a murine T cell lymphoma: requirements for macromolecular synthesis and lack of relationship with cell cycle.鼠T细胞淋巴瘤产生免疫（γ）干扰素：大分子合成的需求及与细胞周期的无关性
Infect Immun. 1983 Aug;41(2):624-30. doi: 10.1128/iai.41.2.624-630.1983.
2
Superinduction of the human interferon-beta promoter.人β-干扰素启动子的超诱导
EMBO J. 1987 Mar;6(3):599-604. doi: 10.1002/j.1460-2075.1987.tb04796.x.
3
Factors influencing the production of interferon from L cells.影响L细胞产生干扰素的因素。
Infect Immun. 1976 Feb;13(2):326-31. doi: 10.1128/iai.13.2.326-331.1976.

本文引用的文献

1
A RICH SOURCE OF MOUSE INTERFERON.小鼠干扰素的丰富来源。
Nature. 1964 Dec 12;204:1114-5. doi: 10.1038/2041114b0.
2
Regulation of cellular interferon production: enhancement by antimetabolites.细胞干扰素产生的调节：抗代谢物的增强作用。
Proc Natl Acad Sci U S A. 1970 Sep;67(1):464-71. doi: 10.1073/pnas.67.1.464.
3
Accentuation of production of human interferon by metabolic inhibitors.代谢抑制剂对人干扰素产生的增强作用。
Proc Soc Exp Biol Med. 1972 Jan;139(1):259-62. doi: 10.3181/00379727-139-36122.
4
Production of high-titered interferon in cultures of human diploid cells.在人二倍体细胞培养物中产生高滴度干扰素。
Antimicrob Agents Chemother. 1972 Dec;2(6):476-84. doi: 10.1128/AAC.2.6.476.
5
Mass production of human interferon in diploid cells stimulated by poly-I:C.在聚肌胞苷酸（poly-I:C）刺激的二倍体细胞中大规模生产人干扰素。
J Gen Virol. 1973 Apr;19(1):1-8. doi: 10.1099/0022-1317-19-1-1.
6
High interferon producing line of transformed murine cells.转化鼠细胞的高干扰素产生系。
J Gen Virol. 1972 Oct;17(1):107-9. doi: 10.1099/0022-1317-17-1-107.
7
The effect of interferon, interferon inducers or interferon induced virus resistance on subsequent interferon production.干扰素、干扰素诱导剂或干扰素诱导的病毒抗性对后续干扰素产生的影响。
J Gen Virol. 1972 May;15(2):119-28. doi: 10.1099/0022-1317-15-2-119.
8
Accentuation of interferon production by metabolic inhibitors and its dependence on protein synthesis.代谢抑制剂对干扰素产生的增强作用及其对蛋白质合成的依赖性。
Virology. 1971 Jun;44(3):503-9. doi: 10.1016/0042-6822(71)90363-1.
9
Distinguishing characteristics of the interferon responses of primary and continuous mouse cell cultures.原代和连续传代小鼠细胞培养物干扰素反应的鉴别特征。
J Gen Virol. 1971 Oct;13(1):35-50. doi: 10.1099/0022-1317-13-1-35.
10
Potentiation of human interferon production by superinduction.通过超诱导增强人干扰素的产生。
J Natl Cancer Inst. 1971 Oct;47(4):757-64.