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Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized.

作者信息

Wagner J G

出版信息

J Pharmacokinet Biopharm. 1973 Apr;1(2):165-73. doi: 10.1007/BF01059628.

DOI:10.1007/BF01059628
PMID:4797185
Abstract
摘要

相似文献

1
Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized.
J Pharmacokinet Biopharm. 1973 Apr;1(2):165-73. doi: 10.1007/BF01059628.
2
Metabolism of clindamycin. I. Absorption and excretion of clindamycin in rat and dog.克林霉素的代谢。I. 大鼠和犬体内克林霉素的吸收与排泄。
J Pharm Sci. 1973 Aug;62(8):1265-9. doi: 10.1002/jps.2600620806.
3
Lincomycin and clindamycin.林可霉素和克林霉素。
Antibiot Chemother (1971). 1978;25:204-16. doi: 10.1159/000401063.
4
Absorption and excretion of clindamycin-2-phosphate in children after intramuscular injection.儿童肌内注射磷酸克林霉素-2后的吸收与排泄
Clin Pharmacol Ther. 1972 Sep-Oct;13(5):704-9. doi: 10.1002/cpt1972135part1704.
5
Clinical pharmacokinetics in infants and children.婴幼儿临床药代动力学
Clin Pharmacokinet. 1976;1(1):2-24. doi: 10.2165/00003088-197601010-00002.
6
[Pharmacokinetics of lincomycin and clindamycin].[林可霉素与克林霉素的药代动力学]
Med Welt. 1976 May 28;27(22):1096-1100.
7
Cellular uptake of clindamycin and lincomycin.克林霉素和林可霉素的细胞摄取。
Br J Exp Pathol. 1984 Dec;65(6):725-30.
8
[The pharmacokinetics of clindamycin in abnormal liver and renal function].[克林霉素在肝肾功能异常时的药代动力学]
Dtsch Med Wochenschr. 1972 Jul 14;97(28):1057-9. doi: 10.1055/s-0028-1107497.
9
Genetic and environmental factors affecting drug response in man.影响人类药物反应的遗传和环境因素。
Fed Proc. 1972 Jul-Aug;31(4):1253-69.
10
Effect of route of administration on drug disposition.给药途径对药物处置的影响。
J Pharmacokinet Biopharm. 1973 Oct;1(5):419-34. doi: 10.1007/BF01059666.

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Within- and between-subject variations in pharmacokinetic parameters of ethanol by analysis of breath, venous blood and urine.通过分析呼气、静脉血和尿液来研究乙醇药代动力学参数的个体内和个体间变异。
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本文引用的文献

1
Biological half-lives of the antibiotic lincomycin observed in repetitive experiments in the same subjects.在同一受试者的重复实验中观察到的抗生素林可霉素的生物半衰期。
Nature. 1965 Jul 10;207(993):201-2. doi: 10.1038/207201a0.
2
Absorption, excretion and half-life of clinimycin in normal adult males.克林霉素在正常成年男性中的吸收、排泄及半衰期
Am J Med Sci. 1968 Jul;256(1):25-37. doi: 10.1097/00000441-196807000-00004.
3
Absorption and elimination of ethosuximide in children.儿童中乙琥胺的吸收与消除
老年人的药代动力学变化。它们会导致药物滥用和依赖吗？
Clin Pharmacokinet. 1996 Nov;31(5):372-85. doi: 10.2165/00003088-199631050-00004.
4
Inter-individual and intra-individual variability of ethanol concentration-time profiles: comparison of ethanol ingestion before or after an evening meal.乙醇浓度-时间曲线的个体间和个体内变异性：晚餐前后乙醇摄入量的比较。
Br J Clin Pharmacol. 1995 Oct;40(4):387-92. doi: 10.1111/j.1365-2125.1995.tb04561.x.
5
Between-subject and within-subject variations in the pharmacokinetics of ethanol.乙醇药代动力学的个体间和个体内变异
Br J Clin Pharmacol. 1994 May;37(5):427-31. doi: 10.1111/j.1365-2125.1994.tb05709.x.
6
Intraindividual variability in theophylline pharmacokinetics: statistical verification in 39 of 60 healthy young adults.
J Pharmacokinet Biopharm. 1982 Apr;10(2):123-34. doi: 10.1007/BF01062330.
7
Assessment of methods to identify sources of interindividual pharmacokinetic variations.个体间药代动力学差异来源识别方法的评估
Clin Pharmacokinet. 1983 Sep-Oct;8(5):378-409. doi: 10.2165/00003088-198308050-00002.
8
A twin study of ethanol metabolism.
Behav Genet. 1985 Mar;15(2):93-109. doi: 10.1007/BF01065891.
9
Stepwise determination of multicompartment disposition and absorption parameters from extravascular concentration-time data. Application to mesoridazine, flurbiprofen, flunarizine, labetalol, and diazepam.从血管外浓度-时间数据逐步确定多室处置和吸收参数。应用于甲砜哒嗪、氟比洛芬、氟桂利嗪、拉贝洛尔和地西泮。
J Pharmacokinet Biopharm. 1991 Aug;19(4):413-55. doi: 10.1007/BF01061665.
10
Pharmacokinetics of isoniazid and some metabolites in man.异烟肼及其某些代谢产物在人体中的药代动力学。
J Pharmacokinet Biopharm. 1976 Aug;4(4):287-325. doi: 10.1007/BF01063121.
J Clin Pharmacol J New Drugs. 1969 Nov-Dec;9(6):393-8.
4
Urinary excretion of ephedrine in man without pH control following oral administration of three commercial ephedrine sulfate preparations.
J Pharm Sci. 1971 Nov;60(11):1629-34. doi: 10.1002/jps.2600601107.
5
Assay of warfarin: a rebuttal.华法林检测：一则反驳
J Pharm Sci. 1971 Aug;60(8):1272-3. doi: 10.1002/jps.2600600845.
6
In vivo and in vitro availability of commercial warfarin tablets.市售华法林片剂的体内和体外生物利用度
J Pharm Sci. 1971 May;60(5):666-77. doi: 10.1002/jps.2600600503.
7
Genetic and environmental factors affecting ethanol metabolism in man.影响人类乙醇代谢的遗传和环境因素。
Clin Pharmacol Ther. 1971 Mar-Apr;12(2):192-201. doi: 10.1002/cpt1971122part1192.
8
Local and systemic tolerance, absorption and excretion of clindamycin hydrochloride after intramuscular administration.肌内注射盐酸克林霉素后的局部及全身耐受性、吸收与排泄
Int Z Klin Pharmakol Ther Toxikol. 1970 Jul;3(3):201-8.
9
Variations in absorption and elimination rates of ethyl alcohol in a single subject.
Res Commun Chem Pathol Pharmacol. 1972 Jul;4(1):61-76.