使用精算分析确定 Kasai 手术治疗胆道闭锁后的生存决定因素。
Determinants of survival after Kasai's operation for biliary atresia using actuarial analysis.
作者信息
Hitch D C, Shikes R H, Lilly J R
出版信息
J Pediatr Surg. 1979 Jun;14(3):310-4. doi: 10.1016/s0022-3468(79)80489-3.
PMID:480093
Abstract
Survival after Kasai's operation for "noncorrectable" biliary atresia is influenced by (1) age, (2) large bile ducts, and (3) concentration of the bile bilirubin. Critical values are: age less than 10.5 wk, any evidence of a large bile duct, and a bile bilirubin concentration greater than 8.8 mg/100 ml. Using these 3 factors, a predictive model is able to identify a favorable group with an 89% expected 4 yr survival.
摘要
对于“不可矫正型”胆道闭锁，Kasai手术后的生存率受以下因素影响：（1）年龄；（2）大胆管情况；（3）胆汁胆红素浓度。临界值分别为：年龄小于10.5周、存在任何大胆管的证据、胆汁胆红素浓度大于8.8mg/100ml。利用这三个因素，一个预测模型能够识别出预期4年生存率为89%的预后良好组。
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