肝门空肠吻合术或胆囊造瘘术治疗肝外胆道闭锁。49例研究。

Hepatic porto-enterostomy or cholecystostomy in the treatment of extrahepatic biliary atresia. A study of 49 cases.

作者信息

Odiévre M, Valayer J, Razemon-Pinta M, Habib E C, Alagille D

出版信息

J Pediatr. 1976 May;88(5):774-9. doi: 10.1016/s0022-3476(76)81113-4.

Abstract

Hepatic porto-enterostomy or cholecystostomy (Kasai's procedure) was successful in restoring bile flow in 31 of 49 patients with "noncorrectable" extrahepatic biliary atresia. However, all but one of the 31 developed acute or chronic complications such as cholangitis, bile peritonitis, or portal hypertension. During a five-year follow-up period, 26 (53%) died while 9 of the 23 survivors continue to manifest chronic or recurrent cholangitis. Thirteen of the 19 survivors who are more than one year of age have developed portal hypertension. These complications limit the prognosis of infants with "noncorrectable" biliary malformations.

摘要

肝门肠吻合术或胆囊造瘘术（Kasai手术）成功恢复了49例“不可矫正”肝外胆道闭锁患者中31例的胆汁流动。然而，这31例中除1例之外，其余均出现了急性或慢性并发症，如胆管炎、胆汁性腹膜炎或门静脉高压。在五年的随访期内，26例（53%）死亡，23例幸存者中有9例继续表现为慢性或复发性胆管炎。19例年龄超过一岁的幸存者中有13例出现了门静脉高压。这些并发症限制了“不可矫正”胆道畸形婴儿的预后。