呼肠孤病毒的诱变特异性
Mutagenic specificity in reovirus.
作者信息
Ray U R, Fields B N
出版信息
J Virol. 1979 Jun;30(3):913-6. doi: 10.1128/JVI.30.3.913-916.1979.
Abstract
Mutagenic specificity in response to chemical mutagens has been observed with certain temperature-sensitive mutants of reovirus type 3. One mutant induced by nitrous acid reverted specifically with nitrous acid. Three nitrosoguanidine-induced mutants reverted after nitrous acid treatment. These findings thus suggest that analysis of chemical induction of reversion from the temperature-sensitive phenotype may be a useful approach for studying the nature of mutation in animal viruses.
摘要
在呼肠孤病毒3型的某些温度敏感突变体中，已观察到对化学诱变剂的诱变特异性。一种由亚硝酸诱导的突变体仅能被亚硝酸特异性回复突变。三种由亚硝基胍诱导的突变体在亚硝酸处理后发生了回复突变。因此，这些发现表明，分析从温度敏感表型化学诱导回复突变，可能是研究动物病毒突变本质的一种有用方法。
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1
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Proc Natl Acad Sci U S A. 1959 Apr;45(4):622-33. doi: 10.1073/pnas.45.4.622.
2
IDENTIFICATION OF THE ALTERED BASES IN MUTATED SINGLE-STRANDED DNA. I. IN VITRO MUTAGENESIS BY HYDROXYLAMINE, ETHYL METHANESULFONATE AND NITROUS ACID.突变单链DNA中碱基改变的鉴定。I. 羟胺、甲基磺酸乙酯和亚硝酸的体外诱变作用
J Mol Biol. 1964 Aug;9:352-63. doi: 10.1016/s0022-2836(64)80212-6.
3
Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA.5-氟尿嘧啶对突变表型的逆转：一种研究信使核糖核酸中核苷酸序列的方法。
Proc Natl Acad Sci U S A. 1962 Apr 15;48(4):532-46. doi: 10.1073/pnas.48.4.532.
4
Production of mutants of tobacco mosaic virus by chemical alteration of its ribonucleic acid in vitro.通过体外化学改变烟草花叶病毒的核糖核酸来产生其突变体。
Nature. 1958 Nov 22;182(4647):1457-8. doi: 10.1038/1821457a0.
5
Isolation and preliminary genetic and biochemical characterization of temperature-sensitive mutants of reovirus.呼肠孤病毒温度敏感突变体的分离及初步遗传与生化特性分析
Virology. 1969 Mar;37(3):335-42. doi: 10.1016/0042-6822(69)90217-7.
6
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Mutat Res. 1968 May-Jun;5(3):359-71. doi: 10.1016/0027-5107(68)90006-7.
7
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Mutat Res. 1968 Sep-Oct;6(2):181-93. doi: 10.1016/0027-5107(68)90033-x.
8
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Cold Spring Harb Symp Quant Biol. 1966;31:699-704. doi: 10.1101/sqb.1966.031.01.089.
9
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Cold Spring Harb Symp Quant Biol. 1966;31:163-72. doi: 10.1101/sqb.1966.031.01.024.
10
Proflavin mutagenesis of bacteria.细菌的原黄素诱变
J Mol Biol. 1974 Oct 15;89(1):17-32. doi: 10.1016/0022-2836(74)90160-0.
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