酿酒酵母中的线粒体诱变。III. 亚硝酸。
Mitochondrial mutagenesis in Saccharomyces cerevisiae. III. Nitrous acid.
作者信息
Baranowska H, Putrament A
出版信息
Mutat Res. 1979 Dec;63(2):291-300. doi: 10.1016/0027-5107(79)90060-5.
PMID:392311
Abstract
Nitrous acid (NA) induced mutations efficiently in mitDNA, conferring resistance to erythromycin and weakly induces mit- mutations. In some strains of yeast it also enhanced rho- mutations. The frequencies of nuclear and mitochondrial mutations induced with NA are compared.
摘要
亚硝酸（NA）能有效地诱导线粒体DNA（mitDNA）发生突变，赋予对红霉素的抗性，并且能微弱地诱导线粒体突变。在一些酵母菌株中，它还会增加ρ-突变。比较了用NA诱导的核突变和线粒体突变的频率。
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