Schlegel J U, Halikiopoulos H L, Prima R
J Urol. 1979 Oct;122(4):447-50. doi: 10.1016/s0022-5347(17)56457-5.
A simple technique for determining effective renal plasma flow, filtration fraction and filtration rate is described. The determination depends upon the use of 131iodine labeled hippuran and 99mtechnetium labeled iron ascorbate or Sn diethylenetriaminepentaacetic acid. The filtration fraction is determined by dividing the corrected uptake for the technetium compound by the corrected uptake for radiohippuran. The uptake is simply determined by the 1 to 2-minute count over the kidneys with background subtraction and taking into account the amount injected. The technique is simple, quick and appears to be a useful clinical tool.
本文描述了一种测定有效肾血浆流量、滤过分数和滤过率的简单技术。该测定方法依赖于使用131碘标记的马尿酸钠和99m锝标记的抗坏血酸铁或二乙三胺五乙酸锡。滤过分数通过将锝化合物的校正摄取量除以放射性马尿酸钠的校正摄取量来确定。摄取量可通过在肾脏上进行1至2分钟的计数并减去本底，同时考虑注入量来简单确定。该技术简单、快速，似乎是一种有用的临床工具。
