Sharda D P, Parvez M, Jain A K, Bhargava N C, Misra S N
Lepr India. 1979 Apr;51(2):203-8.
Fibrinolytic activity was studied in 50 patients of leprosy and 30 healthy individuals who served as control. Fibrinolytic activity was determined by measuring euglobulin lysis. No significant alteration in fibrinolytic activity was observed in patients with non-lepromatous leprosy, the levels being approximately similar to control group. However, fibrinolytic activity was found to be significantly decreased in patients of lepromatous leprosy and lepra reaction group. The observed decrease in fibrinolytic activity can be explained on the basis of presence of tissue destruction and vasculitis seen in leprosy more so in patients with lepromatous leprosy and lepra reaction.
对50例麻风患者和30名作为对照的健康个体进行了纤溶活性研究。通过测量优球蛋白溶解来测定纤溶活性。在非瘤型麻风患者中未观察到纤溶活性有明显改变，其水平与对照组大致相似。然而，发现瘤型麻风患者和麻风反应组患者的纤溶活性显著降低。观察到的纤溶活性降低可以基于麻风病中存在的组织破坏和血管炎来解释，在瘤型麻风患者和麻风反应患者中更是如此。
