Yemul V L, Sengupta S R, Dhole T N
Lepr India. 1983 Jan;55(1):91-4.
Serum alpha one antitrypsin levels were measured in 50 healthy age and sex matched controls with 45 lepromatous leprosy cases and 5 cases of lepra reaction. It was noted that the mean level in healthy controls was 281.00 mg%, while the mean levels in LL patients was 421.00 mg% and in LR 570.00 mg%. The elevation of Alpha one antitrypsin was statistically significant in LL patients. It is possible that the rise is a reaction to release of proteases and or higher complement activity, which are the results of a high bacillary loading to formation of immune complexes.
对50名年龄和性别匹配的健康对照者、45例瘤型麻风患者和5例麻风反应患者测定了血清α1抗胰蛋白酶水平。结果发现，健康对照者的平均水平为281.00mg%，而瘤型麻风患者的平均水平为421.00mg%，麻风反应患者为570.00mg%。瘤型麻风患者的α1抗胰蛋白酶升高具有统计学意义。这种升高可能是对蛋白酶释放和/或更高补体活性的反应，而蛋白酶释放和更高补体活性是高菌量负荷导致免疫复合物形成的结果。
