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[肺诺卡菌病。病例报告(作者译)]

[Pulmonary nocardiosis. A case report (author's transl)].

作者信息

García Rodríguez J A, Martín Luengo F, Villar Galán J L

出版信息

Med Clin (Barc). 1979 Jun 25;73(2):73-6.

PMID:481006
Abstract

Within the genus Nocardia three species are at present considered to have human pathologic interest: N. asteroides, N. brasiliensis, and N. caviae. These species are usually the etiologic agents of at least two clinical pictures: nocardiosis and actinomycetoma. A case of pulmonar nocardiosis in a 62-year-old male is reported. The patient had asthmatic episodes and on several occasions received treatment with corticoids. The clinical picture basically consisted of an impairment of the general condition with respiratory symptomatology and fever of 38 to 39 degrees C. An opaque pleuropulmonary image was observed on the chest X-ray film, and the diagnosis of tuberculosis was initially established. The correct diagnosis was confirmed through the bacteriological examination of the transtracheal aspirate with the isolation of N. asteroides. Treatment with streptomycin, sulfamethoxazole and trimethoprim achieved the clinical and roentgenologic cure of the patient. After 2 months of treatment the clinical manifestations had disappeared and after 5 months the chest X-ray was normal. Some epidemiologic data are reviewed.

摘要

在诺卡氏菌属中,目前认为有三种对人类病理学具有重要意义:星状诺卡氏菌、巴西诺卡氏菌和豚鼠诺卡氏菌。这些菌种通常是至少两种临床病症的病原体:诺卡氏菌病和放线菌性足菌肿。本文报告了一例62岁男性的肺部诺卡氏菌病病例。该患者有哮喘发作史,曾多次接受皮质类固醇治疗。临床表现主要为全身状况不佳,伴有呼吸道症状和38至39摄氏度的发热。胸部X光片显示有不透明的胸膜肺部影像,最初诊断为肺结核。通过经气管抽吸物的细菌学检查并分离出星状诺卡氏菌,确诊了正确的诊断。使用链霉素、磺胺甲恶唑和甲氧苄啶进行治疗,使患者实现了临床和影像学治愈。治疗2个月后临床表现消失,5个月后胸部X光片恢复正常。本文还回顾了一些流行病学数据。

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