Kaufmann R, Hillenkamp F, Wechsung R
Med Prog Technol. 1979 Jun 15;6(3):109-21.
After a short review of the general state of the art of microprobe analysis, recent achievements of a new system, the laser microprobe mass analyzer (LAMMA) are presented. The LAMMA-instrument, which was primarily developed for biomedical purposes, has recently been used on a large variety of specimen, biological, technical, organic and inorganic in nature. Detection limits, mass resolution and reproducibility were improved such that for many elements measurements could be extended down to the subppm range. For bulk analysis, a separate version of the LAMMA-instrument is under development. The examples of LAMMA-applications given in this paper include muscle tissue (physiological cations), uterine tissue (Fe), retina tissues (Na, Mgmg, K, Ca and Ba!), airborne particles (Pb, Fe, Al, Ti, Mn, Ca, Zn), cerebral tissue (Li), and pure cristalline organic materials.
在对微探针分析的总体技术现状进行简要回顾之后，介绍了一种新系统——激光微探针质量分析仪（LAMMA）的近期成果。LAMMA仪器主要是为生物医学目的而开发的，最近已被用于各种性质的样本，包括生物、技术、有机和无机样本。检测限、质量分辨率和重现性都得到了改善，以至于对于许多元素的测量可以扩展到亚ppm范围。对于批量分析，LAMMA仪器的一个单独版本正在开发中。本文给出的LAMMA应用实例包括肌肉组织（生理阳离子）、子宫组织（铁）、视网膜组织（钠、镁、钾、钙和钡！）、空气传播颗粒（铅、铁、铝、钛、锰、钙、锌）、脑组织（锂）以及纯结晶有机材料。
