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规律服用阿司匹林与急性心肌梗死

Regular aspirin intake and acute myocardial infarction.

出版信息

Br Med J. 1974 Mar 9;1(5905):440-3.

PMID:4816857
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1633212/
Abstract

The results of two large independent studies involving a combined total of 776 patients treated in hospital with a discharge diagnosis of acute myocardial infarction and 13,898 patients with other discharge diagnoses showed a negative association between regular aspirin intake and non-fatal myocardial infarction. The data are consistent with the hypothesis that aspirin protects against this disease. Clinical trials are needed to determine whether this hypothesis is correct.

摘要

两项大型独立研究的结果显示,定期服用阿司匹林与非致命性心肌梗死之间呈负相关。这两项研究共涉及776例出院诊断为急性心肌梗死的住院患者以及13898例其他出院诊断的患者。这些数据与阿司匹林可预防该病的假设相一致。需要进行临床试验来确定这一假设是否正确。

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The effect of salicylates on the hemostatic properties of platelets in man.水杨酸盐对人体血小板止血特性的影响。
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A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction.一项关于乙酰水杨酸在心肌梗死死亡率二级预防中的随机对照试验。
Br Med J. 1974 Mar 9;1(5905):436-40. doi: 10.1136/bmj.1.5905.436.
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Impaired platelet-connective-tissue reaction in man after aspirin ingestion.阿司匹林摄入后人体血小板与结缔组织反应受损。
Lancet. 1967 Sep 2;2(7514):495-7. doi: 10.1016/s0140-6736(67)91658-3.