Badaracco M A, Vessey M P
Br Med J. 1974 Feb 9;1(5901):215-7. doi: 10.1136/bmj.1.5901.215.
In 1969 this department reported on 42 women who had developed "idiopathic" venous thromboembolism while using oral contraceptives and 42 women who had developed the disease in the absence of such exposure. We have traced the subsequent history of these women to obtain information about recurrence of the disease.During the follow-up period the risk of recurrence of thromboembolism during pregnancy or the puerperium appeared to be much the same irrespective of whether or not oral contraceptives had been in use at the time of the index attack. Recurrences unassociated with childbearing however, occurred about four times more often among women who had not been using oral contraceptives at the time of the index attack than among women who had been doing so. None of these findings was influenced by the use of oral contraceptives during the follow-up period, since exposure to the preparations was negligible after the index attack.
1969年，该部门报告了42名在使用口服避孕药时发生“特发性”静脉血栓栓塞的女性，以及42名在未接触此类药物的情况下发生该病的女性。我们追踪了这些女性的后续病史，以获取有关该病复发的信息。在随访期间，无论首次发作时是否使用口服避孕药，妊娠或产褥期血栓栓塞复发的风险似乎大致相同。然而，与生育无关的复发在首次发作时未使用口服避孕药的女性中发生的频率比使用口服避孕药的女性高约四倍。这些发现均未受到随访期间使用口服避孕药的影响，因为在首次发作后接触这些药物的情况可忽略不计。
