复杂遗传系统中的选择。I. 三位点对称生存力模型的对称平衡
Selection in complex genetic systems. I. The symmetric equilibria of the three-locus symmetric viability model.
作者信息
Feldman M W, Franklin I, Thomson G J
出版信息
Genetics. 1974 Jan;76(1):135-62. doi: 10.1093/genetics/76.1.135.
Abstract
The symmetric equilibria of the three-locus symmetric viability model are determined and their stability analyzed. For tight linkage there may be four stable equilibria, each characterized by having one pair of complementary chromosomes in high frequencies, with all others low. For looser linkage the only stable symmetric equilibrium is that with complete linkage equilibrium. For intermediate recombination values both types of equilibria may be stable. A new class of equilibria with all pairwise linkage disequilibria zero, but with third order linkage disequilibrium, has been discovered. It may be stable for tight linkage.
摘要
确定了三位点对称生存力模型的对称平衡，并分析了其稳定性。对于紧密连锁，可能存在四个稳定平衡，每个平衡的特征是有一对互补染色体高频存在，其他所有染色体低频存在。对于较松散的连锁，唯一稳定的对称平衡是完全连锁平衡。对于中等重组值，两种类型的平衡都可能是稳定的。已经发现了一类新的平衡，其所有成对连锁不平衡均为零，但存在三阶连锁不平衡。对于紧密连锁，它可能是稳定的。
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The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models.选择与连锁的相互作用。I. 一般考量；杂种优势模型。
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