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一个对称的双基因座育性模型。

A symmetric two-locus fertility model.

作者信息

Feldman M W, Liberman U

出版信息

Genetics. 1985 Jan;109(1):229-53. doi: 10.1093/genetics/109.1.229.

DOI:10.1093/genetics/109.1.229
PMID:3967817
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1202479/
Abstract

A model in which selection is mediated by differential fertilities among the genotypes at two diallelic loci is proposed. Fertility depends only on the number of heterozygous loci participating in the mating. Classes analogous to symmetric equilibria in symmetric viability models are determined explicitly and shown to exhibit stability behavior very different from the viability results. Linkage equilibrium is shown to occur in a relatively asymmetric fashion and to overlap in stability with linkage disequilibrium. In many cases single-locus or two-locus polymorphism is shown to be stable simultaneously with chromosome fixation even under very tight linkage. It is suggested that historical effects may be of great significance in the evolution of systems in which fertility is the primary agent of natural selection.

摘要

提出了一个模型,其中选择是由两个双等位基因位点上基因型之间的不同繁殖力介导的。繁殖力仅取决于参与交配的杂合位点的数量。明确确定了与对称生存力模型中的对称平衡类似的类别,并表明它们表现出与生存力结果非常不同的稳定性行为。连锁平衡以相对不对称的方式出现,并在稳定性上与连锁不平衡重叠。在许多情况下,即使在非常紧密的连锁情况下,单基因座或双基因座多态性也被证明与染色体固定同时稳定。有人提出,历史效应在以繁殖力为自然选择主要因素的系统进化中可能具有重要意义。

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Pleiotropic effects of environment-sensitive genes affecting fitness in relation to postmating reproductive isolation.环境敏感基因的多效性对与交配后生殖隔离相关的适合度的影响
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本文引用的文献

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Dynamics of Correlated Genetic Systems. V. Rates of Decay of Linkage Disequilibria in Experimental Populations of DROSOPHILA MELANOGASTER.相关遗传系统的动力学。五、黑腹果蝇实验种群中连锁不平衡的衰减率。
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Selection in complex genetic systems. I. The symmetric equilibria of the three-locus symmetric viability model.复杂遗传系统中的选择。I. 三位点对称生存力模型的对称平衡
Genetics. 1974 Jan;76(1):135-62. doi: 10.1093/genetics/76.1.135.
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