Smith D A
Genetics. 1974 Jan;76(1):1-17. doi: 10.1093/genetics/76.1.1.
When ascospores from crosses of certain strains were germinated under conditions selective for heterozygosity of complementing markers on one linkage group, a portion of the resulting colonies were also heterozygous for unselected markers on other chromosomes, implying multiple disomy. The frequency of disomy and the pattern of marker homozygosity are consistent with most or all multiple disomics having originated as complete diploids following nondisjunction at meiosis I. The production of diploid ascospores in these strains is apparently under polygenic control. The diploids are highly unstable and do not differ from n+1 disomics in rates and mechanisms of haploidization and mitotic crossing over.
当某些菌株杂交产生的子囊孢子在对一个连锁群上互补标记的杂合性具有选择性的条件下萌发时，一部分产生的菌落对于其他染色体上未选择的标记也是杂合的，这意味着存在多重双体。双体的频率和标记纯合性的模式与大多数或所有多重双体起源于减数分裂I期不分离后形成的完全二倍体一致。这些菌株中二倍体子囊孢子的产生显然受多基因控制。这些二倍体高度不稳定，在单倍体化和有丝分裂交换的速率和机制上与n + 1双体没有差异。
