粗糙脉孢菌的不稳定二倍体及其体细胞行为模型。
Unstable diploids of Neurospora and a model for their somatic behavior.
作者信息
Smith D A
出版信息
Genetics. 1974 Jan;76(1):1-17. doi: 10.1093/genetics/76.1.1.
Abstract
When ascospores from crosses of certain strains were germinated under conditions selective for heterozygosity of complementing markers on one linkage group, a portion of the resulting colonies were also heterozygous for unselected markers on other chromosomes, implying multiple disomy. The frequency of disomy and the pattern of marker homozygosity are consistent with most or all multiple disomics having originated as complete diploids following nondisjunction at meiosis I. The production of diploid ascospores in these strains is apparently under polygenic control. The diploids are highly unstable and do not differ from n+1 disomics in rates and mechanisms of haploidization and mitotic crossing over.
摘要
当某些菌株杂交产生的子囊孢子在对一个连锁群上互补标记的杂合性具有选择性的条件下萌发时，一部分产生的菌落对于其他染色体上未选择的标记也是杂合的，这意味着存在多重双体。双体的频率和标记纯合性的模式与大多数或所有多重双体起源于减数分裂I期不分离后形成的完全二倍体一致。这些菌株中二倍体子囊孢子的产生显然受多基因控制。这些二倍体高度不稳定，在单倍体化和有丝分裂交换的速率和机制上与n + 1双体没有差异。
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本文引用的文献
1
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Genetics. 1956 Mar;41(2):227-41. doi: 10.1093/genetics/41.2.227.
2
Somatic Crossing over and Segregation in Drosophila Melanogaster.果蝇中的体细胞交换与分离
Genetics. 1936 Nov;21(6):625-730. doi: 10.1093/genetics/21.6.625.
3
Pseudo-Wild Types in Neurospora Crassa.粗糙脉孢菌中的假野生型
Proc Natl Acad Sci U S A. 1952 Jul;38(7):569-80. doi: 10.1073/pnas.38.7.569.
4
THE EFFECT OF ULTRAVIOLET LIGHT ON RECOMBINATION IN YEAST.紫外线对酵母重组的影响
Genetics. 1963 Dec;48(12):1701-16. doi: 10.1093/genetics/48.12.1701.
5
Somatic recombination in pseudowild-type cultures of Neurospora crassa.粗糙脉孢菌假野生型培养物中的体细胞重组。
Proc Natl Acad Sci U S A. 1963 Apr;49(4):445-51. doi: 10.1073/pnas.49.4.445.
6
Survival of Serratia marcescens in concentrates and suspensions stored at 5C.粘质沙雷氏菌在5℃储存的浓缩物和悬浮液中的存活情况。
Appl Microbiol. 1958 Jul;6(4):233-5. doi: 10.1128/am.6.4.233-235.1958.
7
Studies of gene mutation in Saccharomyces.酿酒酵母基因突变的研究。
Cold Spring Harb Symp Quant Biol. 1956;21:175-85. doi: 10.1101/sqb.1956.021.01.015.
8
A pericentric inversion in Neurospora, with unstable duplication progeny.脉孢菌中的一种臂间倒位，具有不稳定的重复后代。
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9
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