Rosen H, Ebersold W T
Genetics. 1972 Jun;71(2):247-53. doi: 10.1093/genetics/71.2.247.
A mutant strain of Chlamydomonas reinhardi which is UV sensitive as a result of a single-gene chromosomal mutation has also been found to exhibit reduced recombination. In crosses homozygous for the mutant allele, a reduction in recombination frequency was demonstrated in two different linkage groups and in three different genetic backgrounds. Thus a single mutation affecting UV sensitivity also has a possible effect on recombination. Such a mutant could be analogous to the rec(-) mutants discovered in E. coli and as such be useful in the study of recombination mechanisms. Three additional UV-sensitive isolates were tested. Recombination was not altered in these mutant strains.
莱茵衣藻的一种突变株由于单基因染色体突变而对紫外线敏感,同时也被发现其重组能力降低。在突变等位基因纯合的杂交实验中,在两个不同的连锁群和三种不同的遗传背景下都证明了重组频率的降低。因此,一个影响紫外线敏感性的单一突变也可能对重组产生影响。这样的突变体可能类似于在大肠杆菌中发现的rec(-)突变体,因此在重组机制的研究中可能有用。对另外三个紫外线敏感分离株进行了测试。这些突变株中的重组没有改变。