• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Migratory cell locomotion versus nerve axon elongation: differences based on the effects of lanthanum ion.迁移性细胞运动与神经轴突伸长：基于镧离子作用的差异
J Cell Biol. 1974 Apr;61(1):56-69. doi: 10.1083/jcb.61.1.56.
2
Axon growth: roles of microfilaments and microtubules.轴突生长：微丝和微管的作用
Proc Natl Acad Sci U S A. 1970 Aug;66(4):1206-12. doi: 10.1073/pnas.66.4.1206.
3
Effect of lanthanum-induced blockade of calcium channels on nerve regeneration.镧诱导的钙通道阻滞对神经再生的影响。
J Hirnforsch. 1991;32(2):195-201.
4
Cytochalasin B: effects on membrane ruffling, growth cone and microspike activity, and microfilament structure not due to altered glucose transport.细胞松弛素B：对膜皱褶、生长锥和微刺活动以及微丝结构的影响并非由于葡萄糖转运改变所致。
Dev Biol. 1973 Apr;31(2):413-20. doi: 10.1016/0012-1606(73)90276-5.
5
Adhesion among neural cells of the chick embryo. IV. Role of the cell surface molecule CAM in the formation of neurite bundles in cultures of spinal ganglia.鸡胚神经细胞间的黏附。IV. 细胞表面分子细胞黏附分子（CAM）在脊髓神经节培养物中神经突束形成中的作用。
J Cell Biol. 1978 Nov;79(2 Pt 1):382-93. doi: 10.1083/jcb.79.2.382.
6
Interactions of Schwann cells with neurites and with other Schwann cells involve the calcium-dependent adhesion molecule, N-cadherin.雪旺细胞与神经突以及与其他雪旺细胞之间的相互作用涉及钙依赖性黏附分子N-钙黏蛋白。
J Neurobiol. 1991 Oct;22(7):707-20. doi: 10.1002/neu.480220706.
7
Cell locomotion, nerve elongation, and microfilaments.细胞运动、神经伸长与微丝
Dev Biol. 1973 Feb;30(2):427-40. doi: 10.1016/0012-1606(73)90100-0.
8
Ultrastructure and function of growth cones and axons of cultured nerve cells.培养神经细胞生长锥和轴突的超微结构与功能
J Cell Biol. 1971 Jun;49(3):614-35. doi: 10.1083/jcb.49.3.614.
9
Growth of neurites without filopodial or lamellipodial activity in the presence of cytochalasin B.在细胞松弛素B存在的情况下，神经突在没有丝状伪足或片状伪足活动的情况下生长。
J Cell Biol. 1984 Dec;99(6):2041-7. doi: 10.1083/jcb.99.6.2041.
10
Cell-substratum adhesion of neurite growth cones, and its role in neurite elongation.神经突生长锥与底物的黏附及其在神经突伸长中的作用。
Exp Cell Res. 1979 Nov;124(1):127-38. doi: 10.1016/0014-4827(79)90263-5.

引用本文的文献

1
Mechanisms of neuronal growth cone guidance: an historical perspective.神经元生长锥导向的机制：历史视角。
Dev Neurobiol. 2011 Sep;71(9):795-800. doi: 10.1002/dneu.20908. Epub 2011 Jul 29.
2
Intrinsic and extrinsic determinants of neuronal development: relation to infantile autism.神经元发育的内在和外在决定因素：与婴儿自闭症的关系。
J Autism Dev Disord. 1982 Jun;12(2):115-45. doi: 10.1007/BF01531304.
3
Migration of immature neurons along tangentially oriented fibers in the subpial part of the fetal mouse medulla oblongata.未成熟神经元沿胎鼠延髓软膜下部分切向排列的纤维迁移。
Exp Brain Res. 1989;78(2):290-300. doi: 10.1007/BF00228900.
4
Development of the electromotor system in Torpedo marmorata: cationic staining of the electric organ.电鳐（Torpedo marmorata）中电动系统的发育：电器官的阳离子染色
Cell Tissue Res. 1987 Oct;250(1):115-23. doi: 10.1007/BF00214662.
5
Mode of neuronal migration of the pontine stream in fetal mice.胎鼠脑桥神经元迁移流的迁移模式。
Anat Embryol (Berl). 1990;182(1):11-9. doi: 10.1007/BF00187523.
6
Regulated plasmalemmal expansion in nerve growth cones.神经生长锥中受调控的质膜扩张。
J Cell Biol. 1991 Mar;112(6):1215-27. doi: 10.1083/jcb.112.6.1215.
7
Freeze-fracture studies of the developing cell surface. I. The plasmalemma of the corneal fibroblast.发育中细胞表面的冰冻断裂研究。I. 角膜成纤维细胞的质膜。
J Cell Biol. 1977 Mar;72(3):667-86. doi: 10.1083/jcb.72.3.667.
8
The culture of chick embryo dorsal root ganglionic cells on polylysine-coated plastic.在聚赖氨酸包被的塑料上培养鸡胚背根神经节细胞。
Neurochem Res. 1979 Apr;4(2):155-73. doi: 10.1007/BF00964141.

本文引用的文献

1
STAINING PROPERTIES OF LANTHANUM ON CELL MEMBRANES.镧在细胞膜上的染色特性
Proc Natl Acad Sci U S A. 1965 Feb;53(2):425-30. doi: 10.1073/pnas.53.2.425.
2
Changes in the cross-striations of muscle during contraction and stretch and their structural interpretation.肌肉收缩和伸展过程中横纹的变化及其结构解释。
Nature. 1954 May 22;173(4412):973-6. doi: 10.1038/173973a0.
3
Ionic conductance changes in lobster axon membrane when lanthanum is substituted for calcium.用镧取代钙时龙虾轴突膜的离子电导变化。
J Gen Physiol. 1966 Nov;50(2):461-71. doi: 10.1085/jgp.50.2.461.
4
A side view of moving fibroblasts.移动中的成纤维细胞的侧视图。
Nature. 1969 May 17;222(5194):641-4. doi: 10.1038/222641a0.
5
Permselectivity of a porous phospholipid-cholesterol artificial membrane. Calcium and lanthanum effects.多孔磷脂 - 胆固醇人工膜的通透选择性。钙和镧的影响。
Biochem Biophys Res Commun. 1968 Sep 30;32(6):977-83. doi: 10.1016/0006-291x(68)90124-1.
6
The locomotion of mouse fibroblasts in tissue culture.小鼠成纤维细胞在组织培养中的运动。
Biophys J. 1970 Oct;10(10):980-93. doi: 10.1016/S0006-3495(70)86347-0.
7
The expression of differentiation by chick embryo thyroid in cell culture. I. Functional and fine structural stability in mass and clonal culture.鸡胚甲状腺在细胞培养中的分化表达。I. 群体培养和克隆培养中的功能及精细结构稳定性
J Cell Physiol. 1970 Feb;75(1):33-47. doi: 10.1002/jcp.1040750105.
8
Studies on the active transport of calcium in human red cells.人体红细胞中钙的主动运输研究。
J Gen Physiol. 1969 Dec;54(6):713-29. doi: 10.1085/jgp.54.6.713.
9
Adenosine triphosphate-induced sliding of tubules in trypsin-treated flagella of sea-urchin sperm.三磷酸腺苷诱导海胆精子经胰蛋白酶处理的鞭毛中小管的滑动。
Proc Natl Acad Sci U S A. 1971 Dec;68(12):3092-6. doi: 10.1073/pnas.68.12.3092.
10
Surface movements during the growth of single explanted neurons.单个外植神经元生长过程中的表面运动。
Proc Natl Acad Sci U S A. 1970 Apr;65(4):905-10. doi: 10.1073/pnas.65.4.905.

迁移性细胞运动与神经轴突伸长：基于镧离子作用的差异

Migratory cell locomotion versus nerve axon elongation: differences based on the effects of lanthanum ion.

作者信息

Letourneau P C, Wessells N K

出版信息

J Cell Biol. 1974 Apr;61(1):56-69. doi: 10.1083/jcb.61.1.56.

DOI:10.1083/jcb.61.1.56
PMID:4819307
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2109261/
Abstract

The effects of lanthanum ions (La(+++)) on the locomotion and adhesion of g lial cells and elongating nerve axons are reported. La(+++) increases adhesion of both glia and of nerve growth cones to a plastic substratum. La(+++) also markedly reduces glia locomotion, but it does not inhibit nerve elongation. Electron-opaque deposits are seen on the cell surface and within cytoplasmic vesicles of glia and nerves cultured in a La(+++)-containing medium. Possible modes of action for La(+++) are discussed, particularly the possibilities that Ca(++) fluxes or Ca(++) involvement in adhesion are altered by La(+++). The results are consistent with the hypothesis that cell migration and nerve axon elongation differ in mechanism, with respect to both adhesive interactions and the activity of microfilament systems.

摘要

本文报道了镧离子（La(+++)）对神经胶质细胞运动和黏附以及伸长神经轴突的影响。La(+++)增加了神经胶质细胞和神经生长锥与塑料基质的黏附。La(+++)也显著降低了神经胶质细胞的运动，但不抑制神经轴突的伸长。在含La(+++)的培养基中培养的神经胶质细胞和神经细胞表面及胞质小泡内可见电子不透明沉积物。讨论了La(+++)可能的作用方式，特别是La(+++)改变Ca(++)通量或Ca(++)参与黏附的可能性。这些结果与以下假设一致，即细胞迁移和神经轴突伸长在黏附相互作用和微丝系统活性方面的机制不同。