Lyons J P, Ryder R C, Campbell H, Clarke W G, Gough J
Br J Ind Med. 1974 Jan;31(1):36-44. doi: 10.1136/oem.31.1.36.
36-44. A correlation study of ventilatory, morbid anatomical, and radiological findings 95 deceased coal miners who suffered with simple pneumoconiosis during life was undertaken using the new ILO U/C International Classification of Radiographs of Pneumoconiosis, which now provides for the occurence of irregular opacities in addition to the classical rounded opacities. The study was carried out with a view to ascertaining the frequency of occurrence and the significance of irregular opacities in coalworkers' pneumoconiosis. Two ϰ-ray films with an average interval of 11 years between them were reported on in each case. The results showed that irregular opacities amounting to category 1 or more were present in 20% of the earlier films and in 48% of the later ones. Exceptionally they occured alone but were usually admixed with classical rounded opacities. Irregular opacities correlated positively with the extent of emphysema and the impairment of FEV whereas rounded opacities did not. Possible pathological causes for the irregular opacities are discussed and it is maintained that coalworkers' pneumoconiosis is the most probable one. Finally, it is suggested that the significance of these irregular changes may have been underrated in certain cases hitherto, with consequent underestimation of pneumoconiosis and its related effects. Morphological findings in a typical case showing radiologically mixed irregular and rounded opacities are demonstrated.
36 - 44. 利用国际劳工组织新的U/C型尘肺病X线胸片国际分类法,对95名生前患有单纯尘肺病的已故煤矿工人的通气功能、病理解剖及放射学检查结果进行了相关性研究。该分类法目前除了经典的圆形阴影外,还纳入了不规则阴影。开展这项研究的目的是确定煤工尘肺病中不规则阴影的出现频率及其意义。对每例病例均报告了两张平均间隔11年的X线胸片。结果显示,在早期胸片中,1级及以上的不规则阴影出现在20%的病例中,而在后期胸片中这一比例为48%。不规则阴影极少单独出现,通常与经典的圆形阴影并存。不规则阴影与肺气肿程度及第一秒用力呼气容积(FEV)受损呈正相关,而圆形阴影则不然。文中讨论了不规则阴影可能的病理原因,并认为煤工尘肺病是最有可能的原因。最后指出,迄今为止,在某些病例中这些不规则变化的意义可能被低估了,从而导致对尘肺病及其相关影响的低估。文中展示了一个典型病例的形态学检查结果,该病例的X线表现为不规则阴影与圆形阴影混合存在。