有机溶剂摄取、分布和呼出的模拟与预测

Simulation and prediciton of uptake, distribution, and exhalation of organic solvents.

作者信息

Fiserova-Bergerova V, Vlach J, Singhal K

出版信息

Br J Ind Med. 1974 Jan;31(1):45-52. doi: 10.1136/oem.31.1.45.

DOI:10.1136/oem.31.1.45

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1009542/

Abstract

45-52. Presented here is a theory and mathematical solution of the uptake, distribution, and excretion of inhaled lipid soluble noxious gases, which embraces the effects of metabolism. An electrical analogue was employed to explain the theory, since the analogue is described by the same set of differential equations, and much knowledge is available for the mathematical treatment of electrical networks. The model is used to calculate the uptake and exhalation curves of vapours, to explain what happens to the inhaled vapours in the body, and to predict their cumulation in the body in periodic situations such as occur in industrial exposure.

摘要

45 - 52. 本文提出了一种关于吸入性脂溶性有害气体吸收、分布和排泄的理论及数学解决方案，其中涵盖了代谢的影响。采用了一个电模拟来解释该理论，因为该模拟由同一组微分方程描述，并且有许多关于电网数学处理的知识可用。该模型用于计算蒸汽的吸收和呼出曲线，解释吸入的蒸汽在体内的变化情况，并预测它们在工业暴露等周期性情况下在体内的累积情况。

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本文引用的文献

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Prac Lek. 1955 May;7(3):150-2.

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