Akinyanju O, Ladapo F
Postgrad Med J. 1979 Jun;55(644):400-2. doi: 10.1136/pgmj.55.644.400.
The incidence of biliary tract disease was investigated by oral cholecystography and/or intravenous cholangiography in 77 unselected Nigerians with homozygous sickle-cell disease (SCD). They included 32 males and 45 females with ages ranging from 8 to 31 years. The prevalence of cholelithiasis was 9% with equal sex incidence. The stones were always multiple and 71.4% of them were radio opaque. Visualization and contractility of all gall bladders examined were normal. The only patient with symptoms and signs which suggested biliary tract disease had no radiographic evidence of cholelithiasis and it was impossible to predict the presence of cholelithiasis from the incidence of abdominal crises in the patients. The prevalence of cholelithiasis is significantly less than that reported in American patients with SCD (35%) and different dietary habits are probably responsible for this.
通过口服胆囊造影和/或静脉胆管造影对77例未经挑选的纯合子镰状细胞病（SCD）尼日利亚人进行了胆道疾病发病率调查。他们包括32名男性和45名女性，年龄在8至31岁之间。胆结石的患病率为9%，男女发病率相等。结石总是多发的，其中71.4%不透X线。所有检查的胆囊的显影和收缩功能均正常。唯一有提示胆道疾病症状和体征的患者没有胆结石的影像学证据，而且无法根据患者腹部危象的发生率来预测胆结石的存在。胆结石的患病率明显低于美国SCD患者报告的患病率（35%），不同的饮食习惯可能是造成这种情况的原因。
