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新生活体和死亡小鼠全身钾(39K)的脉冲核磁共振。T1衰减曲线中的双振荡频率。

Pulsed nuclear magnetic resonance of potassium (39K) of whole body live and dead newborn mice. Double oscillation frequencies in T1 decay curves.

作者信息

Cope F W, Damadian R

出版信息

Physiol Chem Phys. 1979;11(2):143-9.

PMID:482386
Abstract

Pulsed nuclear magnetic resonance relaxation curves (T2 and T1) of potassium (39K) have been measured in detail on whole body newborn mice when alive, and on the same mice after death. The T2 curves are simple exponential with respect to time, but are shorter than for 39K in simple solutions. The T1 curves are not exponential decays, but show large oscillations that may be described approximately as the sum of two separate sine waves of different frequencies. Large T1 oscillations of complex waveform were previously observed by us with 39K in cancer tissues. Gyroscopic motion of adsorbed magnetoelectric dipoles is proposed as a possible physical mechanism accounting for the experimental observations.

摘要

已对活体新生小鼠全身以及死后的同一批小鼠详细测量了钾(³⁹K)的脉冲核磁共振弛豫曲线(T2和T1)。T2曲线相对于时间呈简单指数形式,但比³⁹K在简单溶液中的T2曲线短。T1曲线并非指数衰减,而是呈现出大幅振荡,这些振荡大致可描述为两个不同频率的独立正弦波之和。我们之前在癌症组织中观察到³⁹K具有复杂波形的大幅T1振荡。文中提出吸附的磁电偶极子的陀螺运动可能是解释这些实验观测结果的一种物理机制。

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