广岛和长崎原子弹幸存者的衰老。基于恶性肿瘤患者年龄别死亡率的推测。
Aging in Hiroshima and Nagasaki atomic bomb survivors. Speculations based upon the age-specific mortality of persons with malignant neoplasms.
作者信息
Anderson R E, Key C R, Yamamoto T, Thorslund T
出版信息
Am J Pathol. 1974 Apr;75(1):1-11.
Evaluation of 1639 malignant tumors from 3067 autopsies of members of the Extended Life Span Study Sample reveals that death occurs earlier in those persons most heavily irradiated ([unk]100 rad) compared with those persons who were less exposed. This effect is particularly pronounced in the younger age categories and among females and is not attributable to a specific neoplasm. Assuming that a positive correlation exists between aging and the age-specific mortality of persons with neoplasms, it is concluded that this response is consistent with other observations which suggest the presence of accelerated or precocious aging in the most heavily irradiated group of survivors.
对延长寿命研究样本成员的3067例尸检中的1639例恶性肿瘤进行评估后发现，与暴露较少的人相比，辐射剂量最大（≥100拉德）的人死亡时间更早。这种效应在较年轻年龄段和女性中尤为明显，且并非由特定肿瘤所致。假设衰老与患有肿瘤的人的年龄特异性死亡率之间存在正相关关系，那么可以得出结论，这种反应与其他观察结果一致，这些观察结果表明，在辐射剂量最大的幸存者群体中存在加速或早衰现象。
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