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肌肽在初级嗅觉通路中。

Carnosine in the primary olfactory pathway.

作者信息

Margolis F L

出版信息

Science. 1974 May 24;184(4139):909-11. doi: 10.1126/science.184.4139.909.

Abstract

Carnosine (beta-alanyl-L-histidine) is present in mouse olfactory bulbs and nasal olfactory epithelium at concentrations exceeding that previously reported for any brain region of any species. After peripheral deafferentation, carnosine concentrations in the olfactory bulbs decrease to less than 10 percent that of normal, while other amino compounds are unaffected. Carnosine appears to be highly localized to the primary olfactory pathway.

摘要

肌肽(β-丙氨酰-L-组氨酸)在小鼠嗅球和鼻嗅上皮中的浓度超过此前报道的任何物种任何脑区的浓度。外周去传入神经后,嗅球中的肌肽浓度降至正常浓度的10%以下,而其他氨基化合物未受影响。肌肽似乎高度定位于初级嗅觉通路。

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