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采用免疫抑制和血浆置换疗法治疗肺出血肾炎综合征。

Treatment of Goodpasture's syndrome with immunosuppression and plasmapheresis.

作者信息

Finch R A, Rutsky E A, McGowan E, Wilson C B

出版信息

South Med J. 1979 Oct;72(10):1288-90. doi: 10.1097/00007611-197910000-00021.

Abstract

A 14-year-old boy with Goodpasture's syndrome induced by anti-glomerular-basement-membrane (gmb) antibody exhibited declining renal function, in association with a progressive increase in the level of serum anti-GBM antibody. Treatment with prednisone, cyclophosphamide, and plasmapheresis was associated with rapid disappearance of the serum anti-GMB antibody and temporary stabilization of renal function.

摘要

一名14岁患有抗肾小球基底膜(GBM)抗体诱发的Goodpasture综合征的男孩,其肾功能不断下降,同时血清抗GBM抗体水平持续升高。使用泼尼松、环磷酰胺和血浆置换治疗后,血清抗GBM抗体迅速消失,肾功能暂时稳定。

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