免疫抑制治疗和血浆置换后Goodpasture综合征的康复情况。
Recovery from Goodpasture's syndrome after immunosuppressive treatment and plasmapheresis.
作者信息
Lockwood C M, Boulton-Jones J M, Lowenthal R M, Simpson I J, Peters D K
出版信息
Br Med J. 1975 May 3;2(5965):252-4. doi: 10.1136/bmj.2.5965.252.
Abstract
A patient with Goodpasture's syndrome has recovered after treatment with immunosuppressive drugs (cyclophosphamide and prednisolone) and removal of circulating antibodies by plasma exchange. This was performed on seven occasions and seems to have hastened the decline in circulating antibody levels. Undertaken early in the course of the disease plasmapheresis could prove a useful addition to its therapy.
摘要
一名患有肺出血肾炎综合征的患者在接受免疫抑制药物（环磷酰胺和泼尼松龙）治疗以及通过血浆置换去除循环抗体后康复。血浆置换进行了7次，似乎加速了循环抗体水平的下降。在疾病早期进行血浆置换可能是该疾病治疗的一项有益补充。
相似文献
1
Recovery from Goodpasture's syndrome after immunosuppressive treatment and plasmapheresis.免疫抑制治疗和血浆置换后Goodpasture综合征的康复情况。
Br Med J. 1975 May 3;2(5965):252-4. doi: 10.1136/bmj.2.5965.252.
2
Treatment of Goodpasture's syndrome with immunosuppression and plasmapheresis.采用免疫抑制和血浆置换疗法治疗肺出血肾炎综合征。
South Med J. 1979 Oct;72(10):1288-90. doi: 10.1097/00007611-197910000-00021.
3
Failure of plasma exchange and immunosuppression to improve renal function in Goodpasture's syndrome.血浆置换和免疫抑制未能改善肺出血肾炎综合征的肾功能。
Clin Nephrol. 1978 Aug;10(2):71-3.
4
Goodpasture's syndrome--effects of plasmapheresis.肺出血肾炎综合征——血浆置换的效果
Clin Exp Immunol. 1979 May;36(2):244-9.
5
Plasmapheresis and immunosuppressive agents in antibasement membrane antibody-induced Goodpasture's syndrome.血浆置换及免疫抑制剂治疗抗基底膜抗体诱发的肺出血肾炎综合征
Am J Med. 1978 Feb;64(2):354-9. doi: 10.1016/0002-9343(78)90065-7.
6
Transplantation, immunosuppression and plasmapheresis in Goodpasture's syndrome.肺出血肾炎综合征中的移植、免疫抑制及血浆置换
Clin Nephrol. 1978 Mar;9(3):126-8.
7
Immunosuppression and plasma-exchange in the treatment of Goodpasture's syndrome.免疫抑制和血浆置换治疗肺出血肾炎综合征
Lancet. 1976 Apr 3;1(7962):711-5. doi: 10.1016/s0140-6736(76)93089-0.
8
Goodpasture's syndrome with absence of circulating anti-glomerular basement membrane antibodies: a case report.循环抗肾小球基底膜抗体阴性的肺出血肾炎综合征：一例报告
J Med Case Rep. 2016 Jul 27;10:205. doi: 10.1186/s13256-016-0984-6.
9
Antiglomerular basement membrane antibody-mediated glomerulonephritis and Goodpasture's syndrome.抗肾小球基底膜抗体介导的肾小球肾炎和肺出血肾炎综合征。
Medicine (Baltimore). 1979 Sep;58(5):348-61. doi: 10.1097/00005792-197909000-00002.
10
Goodpasture's syndrome: treatment with plasmapheresis, immunosuppression, and anticoagulation.肺出血肾炎综合征：采用血浆置换、免疫抑制及抗凝治疗。
Arch Dis Child. 1983 Sep;58(9):697-702. doi: 10.1136/adc.58.9.697.
引用本文的文献
1
Therapeutic Plasma Exchange: Current and Emerging Applications to Mitigate Cellular Signaling in Disease.治疗性血浆置换：减轻疾病中细胞信号传导的当前及新兴应用
Biomolecules. 2025 Jul 12;15(7):1000. doi: 10.3390/biom15071000.
2
Relationship between anti-GBM antibodies and kidney outcomes in patients with anti-GBM disease.抗肾小球基底膜病患者的抗肾小球基底膜抗体与肾脏结局的关系。
J Nephrol. 2023 Apr;36(3):789-797. doi: 10.1007/s40620-022-01508-5. Epub 2022 Nov 24.
3
Therapeutic apheresis in kidney diseases: an updated review.肾脏病的治疗性血液净化：更新综述。
Ren Fail. 2022 Dec;44(1):842-857. doi: 10.1080/0886022X.2022.2073892.
4
Rituximab therapy in pemphigus and other autoantibody-mediated diseases.利妥昔单抗在天疱疮及其他自身抗体介导疾病中的治疗应用。
F1000Res. 2017 Jan 27;6:83. doi: 10.12688/f1000research.9476.1. eCollection 2017.
5
Role of therapeutic plasmapheresis in ANCA-associated vasculitis.治疗性血浆置换在抗中性粒细胞胞浆抗体相关性血管炎中的作用。
Pediatr Nephrol. 2016 Feb;31(2):217-25. doi: 10.1007/s00467-014-3038-6. Epub 2015 May 19.
6
Rituximab in two cases of Goodpasture's syndrome.利妥昔单抗治疗两例Goodpasture综合征
NDT Plus. 2009 Jun;2(3):225-7. doi: 10.1093/ndtplus/sfp020. Epub 2009 Feb 18.
7
8
Advances in human antiglomerular basement membrane disease.人类抗肾小球基底膜病的研究进展。
Nat Rev Nephrol. 2011 Jul 19;7(12):697-705. doi: 10.1038/nrneph.2011.89.
9
Benefits and limitations of plasmapheresis in renal diseases: an evidence-based approach.血浆置换在肾脏疾病中的益处与局限性：循证医学方法
J Artif Organs. 2011 Mar;14(1):9-22. doi: 10.1007/s10047-010-0529-5. Epub 2010 Dec 10.
10
Advances in apheresis therapy for glomerular diseases.肾小球疾病的血液成分分离疗法进展
Clin Exp Nephrol. 2007 Jun;11(2):122-127. doi: 10.1007/s10157-007-0462-y. Epub 2007 Jun 28.
本文引用的文献
1
GOODPASTURE'S SYNDROME: A CLINICOPATHOLOGIC ENTITY.古德帕斯彻综合征：一种临床病理实体。
Am J Med. 1964 Sep;37:424-44. doi: 10.1016/0002-9343(64)90199-8.
2
Goodpasture's syndrome. Cessation of pulmonary hemorrhage after bilateral nephrectomy.古德帕斯彻综合征。双侧肾切除术后肺出血停止。
Ann Intern Med. 1967 Dec;67(6):1258-64. doi: 10.7326/0003-4819-67-6-1258.
3
The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis.抗肾小球基底膜抗体在人类肾小球肾炎发病机制中的作用。
J Exp Med. 1967 Dec 1;126(6):989-1004. doi: 10.1084/jem.126.6.989.
4
Goodpasture's syndrome: recovery from severe pulmonary hemorrhage after bilateral nephrectomy.古德帕斯彻综合征：双侧肾切除术后严重肺出血的康复情况。
Ann Intern Med. 1971 Aug;75(2):243-50. doi: 10.7326/0003-4819-75-2-243.
5
The presence of anti-glomerular basement membrane antibodies in peripheral blood.外周血中抗肾小球基底膜抗体的存在。
J Immunol. 1969 Dec;103(6):1168-75.
6
Goodpasture's syndrome: failure of nephrectomy to cure pulmonary hemorrhage.肺出血肾炎综合征：肾切除术未能治愈肺出血。
Am J Med. 1973 Oct;55(3):565-70. doi: 10.1016/0002-9343(73)90215-5.
7
Glomerular deposition of properdin in Henoch-Schönlein syndrome and idiopathic focal nephritis.备解素在过敏性紫癜和特发性局灶性肾炎中的肾小球沉积。
Br Med J. 1973 Aug 11;3(5875):326-8. doi: 10.1136/bmj.3.5875.326.
8
Anti-glomerular basement membrane antibody-induced glomerulonephritis.抗肾小球基底膜抗体诱导的肾小球肾炎。
Kidney Int. 1973 Feb;3(2):74-89. doi: 10.1038/ki.1973.14.
Zotero 插件