Harris J R, Gelsthrope K, Doughty R W, Lee D, Morton R S
Acta Derm Venereol. 1975;55(2):127-30.
By means of a standard lymphocyte microcytoxic technique, the tissue types were fully determined in 41 patients with non-gonococcal urethritis and 25 patients with Reiter's syndrome. The antigen HL-A27 was identified in 14 of the patients with Reiter's syndrome and occurred in 3 of the patients with non-gonococcal urethritis. An excess of the genotype HL-A27/W10 was found in patients with Reiter's syndrome. There was no correlation between the duration or the severity of the clinical manifestations of the syndrome and the presence of the antigens. The possibility that the syndrome might result from various pathogenic mechanisms is discussed.
采用标准淋巴细胞微量细胞毒技术，对41例非淋菌性尿道炎患者和25例赖特综合征患者进行了全面的组织分型。在14例赖特综合征患者中鉴定出抗原HL - A27，在3例非淋菌性尿道炎患者中也发现了该抗原。赖特综合征患者中发现基因型HL - A27/W10过量。该综合征临床表现的持续时间或严重程度与抗原的存在之间无相关性。文中讨论了该综合征可能由多种致病机制引起的可能性。
