Holdcroft A, Robinson M J, Gordon H, Whitwam J G
Br Med J. 1974 Jun 1;2(5917):472-5. doi: 10.1136/bmj.2.5917.472.
Observations were made on 26 infants delivered by elective caesarean section under general anaesthesia. A standard anaesthetic technique was employed using a methohexitone, relaxant, nitrous oxide-oxygen sequence with regulated ventilation and the administration of papaveretum after clamping the umbilical cord. In 12 patients the induction dose of methohexitone was 1.4mg/kg and in 14 it was reduced to 1.0 mg/kg. There were no significant differences between the two groups in the clinical status of the mothers, in operative technique and timing, or in the value of PO(2), PCO(2), and pH in the umbilical cord venous blood.The infants whose mothers received the lower dose of methohexitone were in better condition, as assessed by the number needing assisted ventilation, the time taken to establish regular respiration, the Apgar score, and the "Apgar minus colour" score.
对26例在全身麻醉下择期剖宫产分娩的婴儿进行了观察。采用标准麻醉技术，使用甲己炔巴比妥、肌肉松弛剂、按氧化亚氮 - 氧气顺序并进行控制通气，在钳夹脐带后给予罂粟碱。12例患者甲己炔巴比妥的诱导剂量为1.4mg/kg，14例患者的诱导剂量降至1.0mg/kg。两组在母亲的临床状况、手术技术和时机，或脐带静脉血中PO(2)、PCO(2)和pH值方面无显著差异。根据需要辅助通气的人数、建立规律呼吸所需的时间、阿氏评分以及“阿氏评分减去肤色评分”评估，母亲接受较低剂量甲己炔巴比妥的婴儿状况更好。
