Parkin G J, Herlinger H
Gut. 1974 Apr;15(4):268-72. doi: 10.1136/gut.15.4.268.
Intravenous cholangiograms were performed on 100 unselected nonicteric patients using methylglucamine ioglycamide (Biligram). Fifty patients received 10.5 g of contrast medium and 50 received 5.25 g of medium. The contrast medium was injected evenly over five minutes. Side effects were recorded in only 13% of patients and all were mild. Radiographs were taken 10, 30, 60, 90, and 120 minutes after injection and were assessed without the authors being aware of the dose of contrast medium injected.Better statistically significant results were obtained using the higher dose.In patients in whom the gallbladder is present, films taken at 60 minutes and 90 minutes after injection give the maximum available information in 97% of cases. If the gallbladder has not become opacified by 60 minutes, cystic duct obstruction is indicated. In postcholecystectomy patients, films at 30 minutes and 60 minutes after injection give the maximum available information in 95% of cases.
对100例未经挑选的非黄疸患者使用碘甘葡胺（Biligram）进行静脉胆管造影。50例患者接受10.5克造影剂，50例接受5.25克造影剂。造影剂在5分钟内均匀注入。仅13%的患者记录到副作用，且均为轻度。在注射后10、30、60、90和120分钟拍摄X光片，并在作者不知道注入造影剂剂量的情况下进行评估。使用较高剂量获得了更好的统计学显著结果。在有胆囊的患者中，注射后60分钟和90分钟拍摄的片子在97%的病例中能提供最大可用信息。如果胆囊在60分钟时仍未显影，则提示胆囊管梗阻。在胆囊切除术后患者中，注射后30分钟和60分钟拍摄的片子在95%的病例中能提供最大可用信息。
