Tötterman S, Santavirta S
Eur J Radiol. 1981 May;1(2):132-3.
The effect of furosemide on biliary excretion of ioglycamide and bile flow during experimental cholangiography was studied in cholecystectomized and anaesthetized dogs equipped with a Thomas cannula through which the common bile duct could be cannulated. Ioglycamide infusion was started one hour after cannulation of the common bile duct, the infusion rate being 4 micromol/min/kg. Two hours later, 2 mg/kg furosemide was injected intravenously. After furosemide administration biliary ioglycamide concentration and bile flow remained the same as before the furosemide administration. Our evidence suggests that furosemide has no effect on the biliary excretion of ioglycamide or bile flow during ioglycamide cholangiography on dogs.
在实验性胆管造影期间，对行胆囊切除术并麻醉的犬进行了研究，这些犬配备了托马斯套管，通过该套管可对胆总管进行插管，以观察速尿对碘甘酰胺胆汁排泄及胆汁流量的影响。在胆总管插管1小时后开始输注碘甘酰胺，输注速率为4微摩尔/分钟/千克。两小时后，静脉注射2毫克/千克速尿。给予速尿后，胆汁中碘甘酰胺浓度和胆汁流量与给予速尿前相同。我们的证据表明，在犬的碘甘酰胺胆管造影期间，速尿对碘甘酰胺的胆汁排泄或胆汁流量没有影响。
